Gene sets upregulated in CLL by Tact or CD40L stimulation in comparison with PB
| Gene set description . | Number of enriched gene setsa . | Gene sets description . | Genes involved . |
|---|---|---|---|
| Proteasome | 2 | BIOCARTA_PROTEASOME_PATHWAY | PSMA1, PSMA2, PSMA4, PSMA5, PSMD14, PSMD4, PSME2 |
| KEGG_PROTEASOME | |||
| Apoptosis | 2 | KEGG_APOPTOSIS | BCL2L1, BID, BIRC3, FAS, IL1B |
| REACTOME_APOPTOSIS | |||
| Cell cycle | 5 | REACTOME_CELL_CYCLE_MITOTIC | DYNC1I2, NDE1, NUP133, PCNA, PSMA1, PSMA2, PSMA4, PSMA5, PSMD14, PSMD4, PSME2, TUBG1, YWHAG |
| REACTOME_G1_S_TRANSITION | |||
| REACTOME_MITOTIC_M_M_G1_PHASES | |||
| REACTOME_SYNTHESIS_OF_DNA | |||
| REACTOME_S_PHASE | |||
| Cytokine–cytokine receptor interaction | 1 | KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION | CCL20, CCR5, CXCL2, FAS, IL1B, IL7, IL8 |
| Gene set description . | Number of enriched gene setsa . | Gene sets description . | Genes involved . |
|---|---|---|---|
| Proteasome | 2 | BIOCARTA_PROTEASOME_PATHWAY | PSMA1, PSMA2, PSMA4, PSMA5, PSMD14, PSMD4, PSME2 |
| KEGG_PROTEASOME | |||
| Apoptosis | 2 | KEGG_APOPTOSIS | BCL2L1, BID, BIRC3, FAS, IL1B |
| REACTOME_APOPTOSIS | |||
| Cell cycle | 5 | REACTOME_CELL_CYCLE_MITOTIC | DYNC1I2, NDE1, NUP133, PCNA, PSMA1, PSMA2, PSMA4, PSMA5, PSMD14, PSMD4, PSME2, TUBG1, YWHAG |
| REACTOME_G1_S_TRANSITION | |||
| REACTOME_MITOTIC_M_M_G1_PHASES | |||
| REACTOME_SYNTHESIS_OF_DNA | |||
| REACTOME_S_PHASE | |||
| Cytokine–cytokine receptor interaction | 1 | KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION | CCL20, CCR5, CXCL2, FAS, IL1B, IL7, IL8 |
aCurated gene sets, canonical pathways. Only gene sets where at least 5 genes accounted for the enrichment score (leading edge genes) are included. Gene sets specific to nonlymphoid cell types are not shown.