Table 2 Presence or absence of KIT and... | American Society of Hematology

Table 2

Presence or absence of KIT and TET2 mutations in microdissected mast cells and CD15⁺ cells of 5 (A)SM patients with various subtypes of AHNMD

					KIT D816V		TET2 mutation
Patient no.	Disease subtype	BM mast cells, %	Serum tryptase, μg/L	Mutation load of KIT D816V, PB	Mast cells	CD15⁺	Mast cells	CD15⁺
13	ASM-CMML	75	385	5	+	—	+	—
11	ASM-CMML	70	350	5	+	+	+	+
18	ASM-MDS/MPNu	70	120	48	+	+	+	+
19	ASM-MDS/MPNu	40	88	10	+	+	+	+
37	SM-CMML	20	30	0.4	+	—	+	+

					KIT D816V		TET2 mutation
Patient no.	Disease subtype	BM mast cells, %	Serum tryptase, μg/L	Mutation load of KIT D816V, PB	Mast cells	CD15⁺	Mast cells	CD15⁺
13	ASM-CMML	75	385	5	+	—	+	—
11	ASM-CMML	70	350	5	+	+	+	+
18	ASM-MDS/MPNu	70	120	48	+	+	+	+
19	ASM-MDS/MPNu	40	88	10	+	+	+	+
37	SM-CMML	20	30	0.4	+	—	+	+

ASM, aggressive systemic mastocytosis; BM, bone marrow; CMML, chronic myelomonocytic leukemia; MDS, myelodysplastic syndrome; MPNu, myeloproliferative neoplasm unclassified; PB, peripheral blood.

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