Blood tests of value in the diagnostic workup of suspected MDS
| General blood test category . | Specific test . |
|---|---|
| Hematology | • WBC count • WBC full differential count • RBC count • Hemoglobin • Platelet count • RBC indices (mean cell volume) • Reticulocyte count • RBC, leukocyte and platelet morphology |
| Biochemistry | • RBC-folate/serum-folic acid • Cobalamin • Iron • Total iron binding capacity • Ferritin • Lactate dehydrogenase • Bilirubin • Haptoglobin • Direct antiglobulin test (Coombs' test) • C-reactive protein • Alanine transaminase • Aspartate • Transaminase • Alkaline phosphatase • Albumin • Uric acid • Creatinine • Serum protein electrophoresis (serum immunoglobulins) • β2-microglobulin • Thyroid function tests • Hemoglobin electrophoresis |
| Virus | • Anti-HIV • Anti-parvovirus B19 (hypoplastic MDS) • Cytomegalovirus test • Hepatitis B antigen and Antihepatitis C virus in transfusion-dependent patients |
| Other | • Paroxysmal nocturnal hemoglobinuria clone • Specific genetic analyses (in patients in whom a suspicion about inherited bone marrow failure has been raised) |
| General blood test category . | Specific test . |
|---|---|
| Hematology | • WBC count • WBC full differential count • RBC count • Hemoglobin • Platelet count • RBC indices (mean cell volume) • Reticulocyte count • RBC, leukocyte and platelet morphology |
| Biochemistry | • RBC-folate/serum-folic acid • Cobalamin • Iron • Total iron binding capacity • Ferritin • Lactate dehydrogenase • Bilirubin • Haptoglobin • Direct antiglobulin test (Coombs' test) • C-reactive protein • Alanine transaminase • Aspartate • Transaminase • Alkaline phosphatase • Albumin • Uric acid • Creatinine • Serum protein electrophoresis (serum immunoglobulins) • β2-microglobulin • Thyroid function tests • Hemoglobin electrophoresis |
| Virus | • Anti-HIV • Anti-parvovirus B19 (hypoplastic MDS) • Cytomegalovirus test • Hepatitis B antigen and Antihepatitis C virus in transfusion-dependent patients |
| Other | • Paroxysmal nocturnal hemoglobinuria clone • Specific genetic analyses (in patients in whom a suspicion about inherited bone marrow failure has been raised) |
WBC, white blood cell.