Table 3

Results of multivariate analysis for transplantation-related mortality, relapse, leukemia-free, and overall survival by transplantation conditioning regimen

OutcomeHazard ratio (95% confidence interval)P
Myeloablative conditioning regimen   
    Transplantation-related mortality   
        Double UCB vs single UCB 0.81 (0.52-1.28) .37 
    Relapse*   
        Double UCB vs single UCB 0.94 (0.51-1.73) .84 
    Treatment failure (inverse of LFS)   
        Double UCB vs single UCB 0.88 (0.61-1.26) .48 
    Overall mortality   
        Double UCB vs single UCB 0.88 (0.61-1.27) .51 
Reduced-intensity conditioning regimen   
    Transplantation-related mortality   
        Double UCB vs single UCB 1.49 (0.51-4.36) .46 
    Relapse*   
        Double UCB vs single UCB 0.88 (0.47-1.63) .67 
    Treatment failure (inverse of LFS)   
        Double UCB vs single UCB 1.08 (0.64-1.82) .78 
    Overall mortality   
        Double UCB vs single UCB 1.01 (0.57-1.77) .98 
OutcomeHazard ratio (95% confidence interval)P
Myeloablative conditioning regimen   
    Transplantation-related mortality   
        Double UCB vs single UCB 0.81 (0.52-1.28) .37 
    Relapse*   
        Double UCB vs single UCB 0.94 (0.51-1.73) .84 
    Treatment failure (inverse of LFS)   
        Double UCB vs single UCB 0.88 (0.61-1.26) .48 
    Overall mortality   
        Double UCB vs single UCB 0.88 (0.61-1.27) .51 
Reduced-intensity conditioning regimen   
    Transplantation-related mortality   
        Double UCB vs single UCB 1.49 (0.51-4.36) .46 
    Relapse*   
        Double UCB vs single UCB 0.88 (0.47-1.63) .67 
    Treatment failure (inverse of LFS)   
        Double UCB vs single UCB 1.08 (0.64-1.82) .78 
    Overall mortality   
        Double UCB vs single UCB 1.01 (0.57-1.77) .98 

LFS indicates leukemia-free survival; and UCB, umbilical cord blood

*

Model adjusted for age and disease status.

Model adjusted for disease status.

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