Clinical correlates of CD34+
| Covariate . | Age- and sex-adjusted . | Multivariable-adjusted . | ||
|---|---|---|---|---|
| Regression coefficient (SE) . | P . | Regression coefficient (SE) . | P . | |
| Age, y | −0.072 (0.013) | < .0001 | −0.072 (0.013) | < .0001 |
| Female sex | −0.150 (0.025) | < .0001 | −0.129 (0.029) | < .0001 |
| Body mass index | 0.045 (0.013) | < .001 | ||
| Height | −0.019 (0.019) | .333 | ||
| Weight | 0.048 (0.014) | .001 | 0.044 (0.015) | .003 |
| Systolic blood pressure | 0.010 (0.013) | .442 | ||
| Diastolic blood pressure | 0.023 (0.013) | .080 | ||
| Fasting glucose | 0.012 (0.013) | .365 | ||
| Total cholesterol | 0.024 (0.013) | .075 | 0.048 (0.014) | .001 |
| LDL cholesterol | 0.017 (0.013) | .173 | ||
| HDL cholesterol | −0.028 (0.014) | .039 | ||
| Log triglycerides | 0.058 (0.012) | < .0001 | ||
| Hypertension | 0.064 (0.027) | .018 | ||
| Diabetes mellitus | 0.036 (0.039) | .365 | ||
| Cigarette smoking | −0.135 (0.046) | .004 | −0.122 (0.046) | .009 |
| Medications | ||||
| ACE inhibitors | 0.034 (0.031) | .272 | ||
| Angiotensin receptor blockers | 0.023 (0.048) | .631 | ||
| Beta-blockers | 0.042 (0.031) | .174 | ||
| Calcium channel blockers | 0.028 (0.039) | .461 | ||
| Diuretics | 0.063 (0.031) | .047 | ||
| Hormone replacement | −0.013 (0.060) | .833 | ||
| Statins | 0.067 (0.026) | .011 | 0.102 (0.029) | < .001 |
| Covariate . | Age- and sex-adjusted . | Multivariable-adjusted . | ||
|---|---|---|---|---|
| Regression coefficient (SE) . | P . | Regression coefficient (SE) . | P . | |
| Age, y | −0.072 (0.013) | < .0001 | −0.072 (0.013) | < .0001 |
| Female sex | −0.150 (0.025) | < .0001 | −0.129 (0.029) | < .0001 |
| Body mass index | 0.045 (0.013) | < .001 | ||
| Height | −0.019 (0.019) | .333 | ||
| Weight | 0.048 (0.014) | .001 | 0.044 (0.015) | .003 |
| Systolic blood pressure | 0.010 (0.013) | .442 | ||
| Diastolic blood pressure | 0.023 (0.013) | .080 | ||
| Fasting glucose | 0.012 (0.013) | .365 | ||
| Total cholesterol | 0.024 (0.013) | .075 | 0.048 (0.014) | .001 |
| LDL cholesterol | 0.017 (0.013) | .173 | ||
| HDL cholesterol | −0.028 (0.014) | .039 | ||
| Log triglycerides | 0.058 (0.012) | < .0001 | ||
| Hypertension | 0.064 (0.027) | .018 | ||
| Diabetes mellitus | 0.036 (0.039) | .365 | ||
| Cigarette smoking | −0.135 (0.046) | .004 | −0.122 (0.046) | .009 |
| Medications | ||||
| ACE inhibitors | 0.034 (0.031) | .272 | ||
| Angiotensin receptor blockers | 0.023 (0.048) | .631 | ||
| Beta-blockers | 0.042 (0.031) | .174 | ||
| Calcium channel blockers | 0.028 (0.039) | .461 | ||
| Diuretics | 0.063 (0.031) | .047 | ||
| Hormone replacement | −0.013 (0.060) | .833 | ||
| Statins | 0.067 (0.026) | .011 | 0.102 (0.029) | < .001 |
Data are from the subset of subjects without known cardiovascular disease (n = 1595). The CD34+ variable is log transformed. Coefficients (SE) represent change logCD34+ per increase in the value of the covariates shown (by 1 SD for continuous variables). In age- and sex-adjusted models, the association with age is adjusted for sex and the association with sex is adjusted for age.