Nomenclature of B7 family molecules
| CD designation . | Molecule . | “B7” designation . | Eponyms . | “Common” name . | Major ligands . |
|---|---|---|---|---|---|
| CD80 | B7-1 | B7-1 | B7 | CD80 | CD28, CD152 |
| CD86 | B7-2 | B7-2 | — | CD86 | CD28, CD152 |
| CD274 | Programmed cell death ligand 1 | B7-H1 | PD-L1 | PD-L1 | CD279 (PD-1) |
| CD275 | Inducible costimulator ligand | B7-H2 | B7RP-1, B7h, ICOS-L | ICOS-L | CD278 (ICOS) |
| CD276 | B7 homologue 3 | B7-H3 | — | — | ??TLT-2 |
| B7 homologue 4 | B7-H4 | B7S1, B7x | — | ??BTLA | |
| B7 homologue 6 | B7-H6 | — | — | NKp30 | |
| CD273 | Programmed cell death ligand 2 | B7-DC | PD-L2 | PD-L2 | CD279 |
| CD277 | Butyrophilin SF3 | — | BT3.1, BTF5 | — | ? |
| CD designation . | Molecule . | “B7” designation . | Eponyms . | “Common” name . | Major ligands . |
|---|---|---|---|---|---|
| CD80 | B7-1 | B7-1 | B7 | CD80 | CD28, CD152 |
| CD86 | B7-2 | B7-2 | — | CD86 | CD28, CD152 |
| CD274 | Programmed cell death ligand 1 | B7-H1 | PD-L1 | PD-L1 | CD279 (PD-1) |
| CD275 | Inducible costimulator ligand | B7-H2 | B7RP-1, B7h, ICOS-L | ICOS-L | CD278 (ICOS) |
| CD276 | B7 homologue 3 | B7-H3 | — | — | ??TLT-2 |
| B7 homologue 4 | B7-H4 | B7S1, B7x | — | ??BTLA | |
| B7 homologue 6 | B7-H6 | — | — | NKp30 | |
| CD273 | Programmed cell death ligand 2 | B7-DC | PD-L2 | PD-L2 | CD279 |
| CD277 | Butyrophilin SF3 | — | BT3.1, BTF5 | — | ? |
The CD designation is used preferentially in this review.
— indicates no established designation in this category; ?, unknown; and ??, evidence is contested or based on limited date.