Table 2

Total number of erythroblasts in bone marrow and spleen of normal and anemic mouse models

Bone marrow (× 106)Spleen (× 106)
WT (n = 20) 6.4 ± 0.9 0.7 ± 0.1 
4.1R KO (n = 6) 11.3 ± 1.1* 66.5 ± 5.4 
Phlebotomy induced anemia (n = 6) 10.9 ± 1.2* 73.1 ± 3.0 
Hbbth1/th1 (PBS-treated, n = 6) 16.5 ± 0.7 90.4 ± 6.3 
Hbbth1/th1 (transferrin-treated, n = 6) 6.4 ± 1.1 0.8 ± 0.1 
Bone marrow (× 106)Spleen (× 106)
WT (n = 20) 6.4 ± 0.9 0.7 ± 0.1 
4.1R KO (n = 6) 11.3 ± 1.1* 66.5 ± 5.4 
Phlebotomy induced anemia (n = 6) 10.9 ± 1.2* 73.1 ± 3.0 
Hbbth1/th1 (PBS-treated, n = 6) 16.5 ± 0.7 90.4 ± 6.3 
Hbbth1/th1 (transferrin-treated, n = 6) 6.4 ± 1.1 0.8 ± 0.1 

Bone marrow cells are from 2 tibia and 2 femurs.

*

P < .001.

P < .0001.

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