Patient and donor/recipient characteristics
Median patient age, y (range) | 37 (5-71) |
Age groups, n (%) | |
< 20 y | 13 (16) |
20-50 y | 44 (55) |
> 50 y | 23 (29) |
Patient sex, n (%) | |
Male | 52 (65) |
Female | 28 (35) |
Malignant diseases | |
Standard-risk, n (disease status) | 45 |
AML | 34 (CR1 = 21; CR2 = 13) |
ALL | 10 (CR1 = 8; CR2 = 2) |
Plasma cell leukemia | 1 (CR1 = 1) |
High-risk, n (disease status) | 35 |
AML | 11 (CR3 = 2; AD = 9) |
ALL | 5 (CR3 = 1; AD = 4) |
Hodgkin lymphoma | 5 (AD = 5) |
CML | 5 (CP2 = 4; AD = 1) |
Myelodysplastic syndrome | 3 (AD = 3) |
Non-Hodgkin lymphoma | 2 (AD = 2) |
Myelofibrosis | 2 (AD = 2) |
Plasma cell leukemia | 2 (AD = 2) |
Median donor age, y (range) | 39 (16-72) |
Patient sex, n (%) | |
Male | 43 (54) |
Female | 37 (46) |
Donor/recipient relationship, n (%) | |
Sibling | 38 (47) |
Mother | 20 (25) |
Children | 17 (22) |
Father | 4 (5) |
Cousin | 1 (1) |
Donor/recipient sex, n (%) | |
Male/male | 28 (35) |
Female/male | 24 (30) |
Male/female | 15 (19) |
Female/female | 13 (16) |
Donor/recipient CMV serostatus, n (%) | |
Positive/positive | 55 (69) |
Negative/positive | 14 (17) |
Positive/negative | 8 (10) |
Negative/negative | 3 (4) |
ABO match, n (%) | |
Minor mismatched | 12 (15) |
Major mismatched | 30 (38) |
Matched | 38 (47) |
No. of HLA-A, HLA-B, HLA-DRB1 antigens mismatched | |
2 | 28 (35) |
3 | 52 (65) |
Median patient age, y (range) | 37 (5-71) |
Age groups, n (%) | |
< 20 y | 13 (16) |
20-50 y | 44 (55) |
> 50 y | 23 (29) |
Patient sex, n (%) | |
Male | 52 (65) |
Female | 28 (35) |
Malignant diseases | |
Standard-risk, n (disease status) | 45 |
AML | 34 (CR1 = 21; CR2 = 13) |
ALL | 10 (CR1 = 8; CR2 = 2) |
Plasma cell leukemia | 1 (CR1 = 1) |
High-risk, n (disease status) | 35 |
AML | 11 (CR3 = 2; AD = 9) |
ALL | 5 (CR3 = 1; AD = 4) |
Hodgkin lymphoma | 5 (AD = 5) |
CML | 5 (CP2 = 4; AD = 1) |
Myelodysplastic syndrome | 3 (AD = 3) |
Non-Hodgkin lymphoma | 2 (AD = 2) |
Myelofibrosis | 2 (AD = 2) |
Plasma cell leukemia | 2 (AD = 2) |
Median donor age, y (range) | 39 (16-72) |
Patient sex, n (%) | |
Male | 43 (54) |
Female | 37 (46) |
Donor/recipient relationship, n (%) | |
Sibling | 38 (47) |
Mother | 20 (25) |
Children | 17 (22) |
Father | 4 (5) |
Cousin | 1 (1) |
Donor/recipient sex, n (%) | |
Male/male | 28 (35) |
Female/male | 24 (30) |
Male/female | 15 (19) |
Female/female | 13 (16) |
Donor/recipient CMV serostatus, n (%) | |
Positive/positive | 55 (69) |
Negative/positive | 14 (17) |
Positive/negative | 8 (10) |
Negative/negative | 3 (4) |
ABO match, n (%) | |
Minor mismatched | 12 (15) |
Major mismatched | 30 (38) |
Matched | 38 (47) |
No. of HLA-A, HLA-B, HLA-DRB1 antigens mismatched | |
2 | 28 (35) |
3 | 52 (65) |
AD indicates active disease; and CP, chronic phase.