Multivariate analysis of OS and DFS depending on MRD ≥1% at time of CR
| . | OS multivariate . | DFS multivariate . | ||||
|---|---|---|---|---|---|---|
| HR . | 95% CI . | P . | HR . | 95% CI . | P . | |
| NPM1 not detectable | 1 | 1 | ||||
| NPM1/ABL ≤1% | 1.95 | 0.35-10.74 | .443 | 2.97 | 0.61-14.59 | .180 |
| NPM1/ABL >1% | 5.81 | 1.16-29.02 | .032 | 9.58 | 2.04-45.01 | .004 |
| FLT3-ITD mutation | 2.01 | 0.65-6.18 | .226 | 2.33 | 0.91-5.97 | .078 |
| LDH | 0.22 | 0.02-2.05 | .181 | 0.33 | 0.06-2.03 | .429 |
| WBC | 1.89 | 0.51-7.00 | .340 | 2.05 | 064-6.59 | .334 |
| Age | 1.01 | 0.96-1.06 | .807 | 1.02 | 0.99-1.07 | .223 |
| . | OS multivariate . | DFS multivariate . | ||||
|---|---|---|---|---|---|---|
| HR . | 95% CI . | P . | HR . | 95% CI . | P . | |
| NPM1 not detectable | 1 | 1 | ||||
| NPM1/ABL ≤1% | 1.95 | 0.35-10.74 | .443 | 2.97 | 0.61-14.59 | .180 |
| NPM1/ABL >1% | 5.81 | 1.16-29.02 | .032 | 9.58 | 2.04-45.01 | .004 |
| FLT3-ITD mutation | 2.01 | 0.65-6.18 | .226 | 2.33 | 0.91-5.97 | .078 |
| LDH | 0.22 | 0.02-2.05 | .181 | 0.33 | 0.06-2.03 | .429 |
| WBC | 1.89 | 0.51-7.00 | .340 | 2.05 | 064-6.59 | .334 |
| Age | 1.01 | 0.96-1.06 | .807 | 1.02 | 0.99-1.07 | .223 |