Clinical course of congenital AML cases with t(8;16)(p11;p13) reaching spontaneous remission
| Case no. . | Age at Dx (d) . | Initial Dx . | Time to CR (mo) . | Event (time from Dx in mo) . | Further course . | OS (y) . |
|---|---|---|---|---|---|---|
| 41 | 1 | Disseminated myelosarcoma | 12 | — | CCR | 5.0* |
| 35 | 3 | AML | 2 | Unrelated AML (48) | Ct, died of sepsis | 4.1 |
| 37 | 7 | AML | 3 | — | CCR | 2.0* |
| 28 | 9 | AML | 2 | Relapse (8) | Ct | 1.8 |
| Second relapse | SCT | |||||
| Third relapse | Died | |||||
| 40 | 10 | AML | 4 | — | CCR | 0.9* |
| 34 | 19 | AML | 2 | Relapse (9) | Ct | 7.0* |
| 62 | 30 | AML | 2 | Relapse (24) | Ct | 3.8* |
| Second relapse | Ct |
| Case no. . | Age at Dx (d) . | Initial Dx . | Time to CR (mo) . | Event (time from Dx in mo) . | Further course . | OS (y) . |
|---|---|---|---|---|---|---|
| 41 | 1 | Disseminated myelosarcoma | 12 | — | CCR | 5.0* |
| 35 | 3 | AML | 2 | Unrelated AML (48) | Ct, died of sepsis | 4.1 |
| 37 | 7 | AML | 3 | — | CCR | 2.0* |
| 28 | 9 | AML | 2 | Relapse (8) | Ct | 1.8 |
| Second relapse | SCT | |||||
| Third relapse | Died | |||||
| 40 | 10 | AML | 4 | — | CCR | 0.9* |
| 34 | 19 | AML | 2 | Relapse (9) | Ct | 7.0* |
| 62 | 30 | AML | 2 | Relapse (24) | Ct | 3.8* |
| Second relapse | Ct |
AML, acute myeloid leukemia; CCR, continuous complete remission; CR, complete remission; Ct, chemotherapy; Ds, diagnosis; no., number; SCT, stem cell transplantation; y, years.
Patient was alive at last follow-up.