Comparison of the frequencies of HLA-DRB1*1602 and HLA-DQB1*0502 between patients and controls
| HLA . | Allele frequency . | OR . | 95% CI . | P . | Pc . | |
|---|---|---|---|---|---|---|
| Patient (n = 17) . | Control (n = 102) . | |||||
| A*02:03 | 0.235 | 0.064 | 4.52 | (1.54-13.14) | .0040 | .0645 |
| B*40:01 | 0.382 | 0.201 | 2.46 | (1.06-5.68) | .0196 | .6664 |
| DRB1*04:05 | 0.176 | 0.069 | 2.91 | (0.91-9.00) | .0472 | 1.3216 |
| DRB1*08:03 | 0.000 | 0.118 | 0.00 | (0-1.15) | .0306 | .8568 |
| DRB1*09:01 | 0.029 | 0.172 | 0.15 | (0.01-1.05) | .0326 | .9128 |
| DRB1*15:02 | 0.118 | 0.010 | 13.47 | (2.00-111.44) | .0043 | .1204 |
| DRB1*16:02 | 0.441 | 0.083 | 8.68 | (3.47-21.90) | 1.1 × 10−6 | 3.08 × 10−5 |
| DQB1*03:03 | 0.029 | 0.172 | 0.15 | (0.01-1.05) | .0325 | .4550 |
| DQB1*04:01 | 0.176 | 0.059 | 3.43 | (1.05-10.91) | .0282 | .3948 |
| DQB1*05:02 | 0.500 | 0.123 | 7.16 | (3.02-17.05) | 1 × 10−7 | 1.4 × 10−6 |
| HLA . | Allele frequency . | OR . | 95% CI . | P . | Pc . | |
|---|---|---|---|---|---|---|
| Patient (n = 17) . | Control (n = 102) . | |||||
| A*02:03 | 0.235 | 0.064 | 4.52 | (1.54-13.14) | .0040 | .0645 |
| B*40:01 | 0.382 | 0.201 | 2.46 | (1.06-5.68) | .0196 | .6664 |
| DRB1*04:05 | 0.176 | 0.069 | 2.91 | (0.91-9.00) | .0472 | 1.3216 |
| DRB1*08:03 | 0.000 | 0.118 | 0.00 | (0-1.15) | .0306 | .8568 |
| DRB1*09:01 | 0.029 | 0.172 | 0.15 | (0.01-1.05) | .0326 | .9128 |
| DRB1*15:02 | 0.118 | 0.010 | 13.47 | (2.00-111.44) | .0043 | .1204 |
| DRB1*16:02 | 0.441 | 0.083 | 8.68 | (3.47-21.90) | 1.1 × 10−6 | 3.08 × 10−5 |
| DQB1*03:03 | 0.029 | 0.172 | 0.15 | (0.01-1.05) | .0325 | .4550 |
| DQB1*04:01 | 0.176 | 0.059 | 3.43 | (1.05-10.91) | .0282 | .3948 |
| DQB1*05:02 | 0.500 | 0.123 | 7.16 | (3.02-17.05) | 1 × 10−7 | 1.4 × 10−6 |
P values were estimated by the Mantel-Haenszel χ2 or Fisher exact test. Alleles are listed as P < .05. Pc values were obtained by multiplying the P values by the number of alleles at each locus represented in the samples (HLA-A: 16 alleles, HLA-B :34 alleles, HLA-DRB1: 28 alleles, and HLA-DQB1: 14 alleles).