Ligand response categorization for AML samples
| Ligand parameter (N) . | Response* at dose 1/2 (%) . | Response† at dose 3 (%) . | No response (%) . |
|---|---|---|---|
| G-CSF | |||
| pY-Stat3 (132) | 44 (33) | 26 (20) | 62 (47) |
| pS-Stat3 (128) | 7 (5.5) | 18 (14) | 103 (80.5) |
| pY-Stat5 (116) | 28 (24) | 24 (21) | 64 (55) |
| IL-6 | |||
| pY-Stat3 (138) | 23 (16.5) | 37 (27) | 78 (56.5) |
| pS-Stat3 (135) | 2 (1.5) | 6 (4.5) | 127 (94) |
| pY-Stat5 (122) | 1 (1) | 1 (1) | 120 (98) |
| Ligand parameter (N) . | Response* at dose 1/2 (%) . | Response† at dose 3 (%) . | No response (%) . |
|---|---|---|---|
| G-CSF | |||
| pY-Stat3 (132) | 44 (33) | 26 (20) | 62 (47) |
| pS-Stat3 (128) | 7 (5.5) | 18 (14) | 103 (80.5) |
| pY-Stat5 (116) | 28 (24) | 24 (21) | 64 (55) |
| IL-6 | |||
| pY-Stat3 (138) | 23 (16.5) | 37 (27) | 78 (56.5) |
| pS-Stat3 (135) | 2 (1.5) | 6 (4.5) | 127 (94) |
| pY-Stat5 (122) | 1 (1) | 1 (1) | 120 (98) |