Hematological values in WT, CIP4 KO, and WAS KO C57Bl/6 mice
| . | WBC (k/uL) . | Neutro (k/uL) . | Lym (k/uL) . | Hb (g/dL) . | MCV (fL) . | Plt (k/uL) . | MPV (fL) . |
|---|---|---|---|---|---|---|---|
| WT | 16.91 ± 1.8 | 3.29 ± 0.4 | 12.5 ± 1.3 | 14.8 ± 0.7 | 43.8 ± 0.4 | 731 ± 27 | 4.6 ± 0.1 |
| CIP4 KO | 16.8 ± 0.9 | 2.77 ± 0.3 | 13 ± 0.7 | 14.5 ± 0.8 | 48.4 ± 1.3 | 457 ± 40 | 4.4 ± 0.1 |
| WASP KO | 11.8 ± 1.7 | 1.85 ± 0.4 | 9.06 ± 1.2 | 10.7 ± 08 | 48.1 ± 1.1 | 418 ± 61 | 4.55 ± 0.1 |
| . | WBC (k/uL) . | Neutro (k/uL) . | Lym (k/uL) . | Hb (g/dL) . | MCV (fL) . | Plt (k/uL) . | MPV (fL) . |
|---|---|---|---|---|---|---|---|
| WT | 16.91 ± 1.8 | 3.29 ± 0.4 | 12.5 ± 1.3 | 14.8 ± 0.7 | 43.8 ± 0.4 | 731 ± 27 | 4.6 ± 0.1 |
| CIP4 KO | 16.8 ± 0.9 | 2.77 ± 0.3 | 13 ± 0.7 | 14.5 ± 0.8 | 48.4 ± 1.3 | 457 ± 40 | 4.4 ± 0.1 |
| WASP KO | 11.8 ± 1.7 | 1.85 ± 0.4 | 9.06 ± 1.2 | 10.7 ± 08 | 48.1 ± 1.1 | 418 ± 61 | 4.55 ± 0.1 |
CIP4 KO and WASP KO mice are thrombocytopenic. Values shown are average ± standard error of the mean. A minimum of 8 mice were analyzed per group. Similar to WASP KO mice, CIP4 KO mice showed thrombocytopenia (P < .05 by analysis of variance).
Hb, hemoglobin; lym, lymphocytes; MCV, mean corpuscular volume; MPV, mean platelet volume; Plt, platelets; WBC, white blood cells.