Transplantation procedures
| Patient no . | Age at HCT, y . | Type of conditioning . | Conditioning regimen . | Graft HLA match* . | Graft source . | Relationship . |
|---|---|---|---|---|---|---|
| 1 | 0.42 | MAC | Bu, Mel, ATG | 5/6 | Cord | Unrelated |
| 2 | 0.58 | MAC | Bu, Cy, ATG, Etop | 6/6 | Cord | Unrelated |
| 3 | 1 | MAC | Bu, Cy, ATG | 7/8 | BM | Unrelated |
| 4 | 4 | MAC | Bu, Cy, ATG | 10/10 | BM | Unrelated |
| 5 | 5 | MAC | Bu, Flu, ATG | 6/6 | Cord | Unrelated |
| 6 | 10 | MAC | Bu, Cy, ATG | 6/6 | BM | Unrelated |
| 7 | 14 | MAC | Bu, Cy, ATG, Etop | 7/8 | PBSCs | Unrelated |
| 8 | 1 | Intermediate | TBI (6 Gy), Flu, Cy, Mel (80 mg/m2) | 7/8 | Cord | Unrelated |
| 9 | 0.40 | RIC | Alem, Flu, Mel | 8/8 | BM | Unrelated |
| 10 | 0.98 | RIC | Alem, Flu, Mel | 9/10 | BM | Unrelated |
| 11 | 2 | RIC | Alem, Flu, Mel | 9/10 | BM | Unrelated |
| 12 | 3 | RIC | Alem, Flu, Mel | 9/10 | Cord | Unrelated |
| 13 | 3 | RIC | Alem, Flu, Mel | 8/8 | BM | Unrelated |
| 14 | 3 | RIC | Alem, Flu, Mel | 10/10 | BM | Unrelated |
| 15 | 4 | RIC | Alem, Flu, Mel | 8/8 | PBSCs | Maternal |
| 16 | 7 | RIC | Alem, Flu, Treo, Thio | 10/10 | PBSCs | Unrelated |
| 17 | 9 | RIC | Alem, Flu, Mel | 7/8 | BM | Unrelated |
| 18 | 11 | RIC | Alem, Flu, Mel | 8/8 | BM | Unrelated |
| 19 | 19 | RIC | Alem, Flu, Mel | 10/10 | BM | Sibling |
| Patient no . | Age at HCT, y . | Type of conditioning . | Conditioning regimen . | Graft HLA match* . | Graft source . | Relationship . |
|---|---|---|---|---|---|---|
| 1 | 0.42 | MAC | Bu, Mel, ATG | 5/6 | Cord | Unrelated |
| 2 | 0.58 | MAC | Bu, Cy, ATG, Etop | 6/6 | Cord | Unrelated |
| 3 | 1 | MAC | Bu, Cy, ATG | 7/8 | BM | Unrelated |
| 4 | 4 | MAC | Bu, Cy, ATG | 10/10 | BM | Unrelated |
| 5 | 5 | MAC | Bu, Flu, ATG | 6/6 | Cord | Unrelated |
| 6 | 10 | MAC | Bu, Cy, ATG | 6/6 | BM | Unrelated |
| 7 | 14 | MAC | Bu, Cy, ATG, Etop | 7/8 | PBSCs | Unrelated |
| 8 | 1 | Intermediate | TBI (6 Gy), Flu, Cy, Mel (80 mg/m2) | 7/8 | Cord | Unrelated |
| 9 | 0.40 | RIC | Alem, Flu, Mel | 8/8 | BM | Unrelated |
| 10 | 0.98 | RIC | Alem, Flu, Mel | 9/10 | BM | Unrelated |
| 11 | 2 | RIC | Alem, Flu, Mel | 9/10 | BM | Unrelated |
| 12 | 3 | RIC | Alem, Flu, Mel | 9/10 | Cord | Unrelated |
| 13 | 3 | RIC | Alem, Flu, Mel | 8/8 | BM | Unrelated |
| 14 | 3 | RIC | Alem, Flu, Mel | 10/10 | BM | Unrelated |
| 15 | 4 | RIC | Alem, Flu, Mel | 8/8 | PBSCs | Maternal |
| 16 | 7 | RIC | Alem, Flu, Treo, Thio | 10/10 | PBSCs | Unrelated |
| 17 | 9 | RIC | Alem, Flu, Mel | 7/8 | BM | Unrelated |
| 18 | 11 | RIC | Alem, Flu, Mel | 8/8 | BM | Unrelated |
| 19 | 19 | RIC | Alem, Flu, Mel | 10/10 | BM | Sibling |
Bu indicates busulfan; Mel, melphalan; ATG, antithymocyte globulin; Cy, cyclophosphamide; Etop, etoposide; Flu, fludarabine; Alem, alemtuzumab; Treo, treosulfan; Thio, thiotepa; and PBSCs, peripheral blood stem cells.
Six to 10 alleles (HLA-A, HLA-B, HLA-C, HLA-DRB1, or HLA-DQB1).