Thromboembolic events
| Patient no. . | Event . | Baseline platelet count* . | Platelet count prior to/day of the event . | Maximum platelet count† . | Days to onset . | Outcome . |
|---|---|---|---|---|---|---|
| 1 | TIA | 13 | 27 | 301 | 59 | Resolved |
| 2 | PE | 15 | 407 | 407 | 58 | Resolved |
| 3 | DVT | 23 | 248 | 577 | 387 | Resolved |
| 4 | CNS ischemia | 25 | 60 | 122 | 971 | Not resolved |
| Subclavian/brachial vein thrombosis | Unknown | 981 | Not resolved | |||
| 5 | DVT | 26 | 220 | 482 | 134 | Resolved‡ |
| MI | 420 | 362 | Resolved | |||
| DVT | 482 | 387 | Resolved | |||
| 6 | MI | 21 | 197 | 364 | 476 | Resolved |
| 7 | PE | 9 | 246 | 246 | 143 | Resolved‡ |
| 8 | DVT | 15 | 61 | 108 | 114 | Resolved |
| 9 | DVT | 13 | 40 | 55 | 279 | Not resolved |
| 10 | MI | 23 | 146 | 208 | 761 | Resolved |
| 11 | Cerebral infarction | 7 | 143 | 324 | 300 | Resolved‡ |
| 12 | Cerebral infarction | 25 | 219 | 476 | 244 | Resolved‡ |
| 13 | PE | 29 | 94 | 304 | 215 | Resolved |
| DVT | 228 | 304 | 229 | Resolved | ||
| 14 | Balance disorder, speech disorder, dizziness (suspected PRIND) | 14 | 14 | 44 | 1 | Resolved |
| 15 | DVT (8 d posttherapy) | 6 | 28 | 40 | 45 | Resolving |
| 16 | DVT (7 d posttherapy) | 23 | 214 | 465 | 57 | Resolved |
| Patient no. . | Event . | Baseline platelet count* . | Platelet count prior to/day of the event . | Maximum platelet count† . | Days to onset . | Outcome . |
|---|---|---|---|---|---|---|
| 1 | TIA | 13 | 27 | 301 | 59 | Resolved |
| 2 | PE | 15 | 407 | 407 | 58 | Resolved |
| 3 | DVT | 23 | 248 | 577 | 387 | Resolved |
| 4 | CNS ischemia | 25 | 60 | 122 | 971 | Not resolved |
| Subclavian/brachial vein thrombosis | Unknown | 981 | Not resolved | |||
| 5 | DVT | 26 | 220 | 482 | 134 | Resolved‡ |
| MI | 420 | 362 | Resolved | |||
| DVT | 482 | 387 | Resolved | |||
| 6 | MI | 21 | 197 | 364 | 476 | Resolved |
| 7 | PE | 9 | 246 | 246 | 143 | Resolved‡ |
| 8 | DVT | 15 | 61 | 108 | 114 | Resolved |
| 9 | DVT | 13 | 40 | 55 | 279 | Not resolved |
| 10 | MI | 23 | 146 | 208 | 761 | Resolved |
| 11 | Cerebral infarction | 7 | 143 | 324 | 300 | Resolved‡ |
| 12 | Cerebral infarction | 25 | 219 | 476 | 244 | Resolved‡ |
| 13 | PE | 29 | 94 | 304 | 215 | Resolved |
| DVT | 228 | 304 | 229 | Resolved | ||
| 14 | Balance disorder, speech disorder, dizziness (suspected PRIND) | 14 | 14 | 44 | 1 | Resolved |
| 15 | DVT (8 d posttherapy) | 6 | 28 | 40 | 45 | Resolving |
| 16 | DVT (7 d posttherapy) | 23 | 214 | 465 | 57 | Resolved |
CNS indicates central nervous system; DVT, deep vein thrombosis; MI, myocardial infarction; PE, pulmonary embolism; PRIND, prolonged reversible ischemic neurologic deficit; and TIA, transient ischemic event.
Baseline platelet count of the study in which the patient was first exposed to eltrombopag.
Maximum platelet count includes platelet counts across studies while exposed to eltrombopag (ie, prior study and EXTEND study).
Events reported as resolved with sequelae.