Table 1 Diagnostic characteristics in... | American Society of Hematology

Table 1

Diagnostic characteristics in the CDA III Swedish family

	Sex	Bone marrow morphology*	Hb, g/L†	Haptoglobin, g/L‡	LDH, µkat/L	Thymidine kinase§	CDA III\|\|
III:6	M	+	143	<0.1	5.2	52.5	+
III:9	M	−	ND	ND	ND	1.5	−
III:10	M	+	107	<0.1	5.8	36.5	+
III:12	F	−	ND	ND	ND	1.4	−
III:14	M	+	116	0.1	4.3	18.1	+
III:18	M	−	162	0.6	2.7	2.6	−
III:20	F	+	128	<0.1	6.3	36.2	+
IV:2	F	+	80	<0.1	5.3	27.9	+
IV:4	F	+	126	<0.1	8.5	250.0	+
IV:5	M	−	149	1.6	3.1	1.9	−
IV:7	F	+	105	<0.1	8.0	39.1	+
IV:8	M	+	157	<0.1	6.8	37.7	+
IV:10	M	+	107	<0.1	6.2	46.5	+
IV:12IV:12	M	+	ND	ND	ND	56.8	+
IV:14	M	−	153	1.8	2.0	2.2	−
IV:15	M	+	146	<0.1	6.2	28.9	+
IV:17	M	+	129	<0.1	6.2	59.1	+
IV:20	F	+	120	<0.1	4.8	53.3	+
IV:21	F	−	135	1.1	1.9	2.7	−
IV:22	M	−	154	0.6	2	4.5	−
IV:24	F	ND	105	<0.1	ND	65.0	+
IV:26	F	+	114	<0,1	6.1	62.3	+
V:1	M	+	118	<0.1	5.7	43.6	+
V:3	M	+	127	<0.1	7.1	75.0	+
V:4	M	−	145	0.5	2.8	ND	−
V:5	M	+	106	<0.1	6.8	64.3	+
V:7	F	+	94	<0.1	7.7	149.0	+
V:8	F	−	107	0.5	2.4	1.7	−
V:9	M	+	135	<0.1	6.3	65,6	+
V:12	F	ND	114	<0.1	6.7	184.0	+
V:13	F	−	145	1.9	2.0	2.6	−
V:14	M	+	113	<0.1	5.7	41.9	+
V:17	M	−	130	0.6	2.9	1.0	−
V:18	F	−	136	1.0	2.0	3.4	−
V:19	F	ND	153	0.7	2.1	4.0	−
V:20	M	ND	158	1.0	ND	3.3	−
V:22	F	+	121	<0.1	6.1	89.0	+
V:23	M	+	135	<0.1	6.4	139.0	+
V:24	M	ND	105	<0.1	ND	52.3	+
V:26	M	ND	120	<0.1	ND	108.0	+
V:27	M	ND	147	0.6	2.7	5.0	−
V:28	M	ND	145	0.3	3.1	8.0	−
V:30	F	ND	109	<0.1	4.1	120.0	+
V:31	M	ND	118	0.8	ND	3.8	−
V:32	M	ND	127	ND	3.4	7.0	−
V:33	F	+	119	0.1	4.3	18.5	+
V:35	M	ND	ND	<0.1	ND	69.0	+
V:36	F	+	124	<0.1	8.3	167.0	+
V:38	F	−	138	2,6	2.7	6.4	−
VI:1	F	ND	102	<0.1	7.5	279.0	+
VI:2	F	ND	133	1.22	2.2	30.0	−
VI:3	F	ND	114	1.87	2.6	ND	−
VI:4	M	+	123	<0.1	10.0	ND	+
VI:5	M	ND	149	0.53	3.3	ND	−
VI:6	F	ND	116	<0.1	5.9	116	+
VI:7	F	ND	109	<0.1	6.6	120	+
VI:8	M	ND	125	ND	4.6	134	+
VI:10	M	+	108	<0.1	5.8	286	+
VI:11	F	ND	115	ND	5.3	102	+
VI:14	F	ND	107	<0.1	8.8	ND	+

	Sex	Bone marrow morphology*	Hb, g/L†	Haptoglobin, g/L‡	LDH, µkat/L	Thymidine kinase§	CDA III\|\|
III:6	M	+	143	<0.1	5.2	52.5	+
III:9	M	−	ND	ND	ND	1.5	−
III:10	M	+	107	<0.1	5.8	36.5	+
III:12	F	−	ND	ND	ND	1.4	−
III:14	M	+	116	0.1	4.3	18.1	+
III:18	M	−	162	0.6	2.7	2.6	−
III:20	F	+	128	<0.1	6.3	36.2	+
IV:2	F	+	80	<0.1	5.3	27.9	+
IV:4	F	+	126	<0.1	8.5	250.0	+
IV:5	M	−	149	1.6	3.1	1.9	−
IV:7	F	+	105	<0.1	8.0	39.1	+
IV:8	M	+	157	<0.1	6.8	37.7	+
IV:10	M	+	107	<0.1	6.2	46.5	+
IV:12IV:12	M	+	ND	ND	ND	56.8	+
IV:14	M	−	153	1.8	2.0	2.2	−
IV:15	M	+	146	<0.1	6.2	28.9	+
IV:17	M	+	129	<0.1	6.2	59.1	+
IV:20	F	+	120	<0.1	4.8	53.3	+
IV:21	F	−	135	1.1	1.9	2.7	−
IV:22	M	−	154	0.6	2	4.5	−
IV:24	F	ND	105	<0.1	ND	65.0	+
IV:26	F	+	114	<0,1	6.1	62.3	+
V:1	M	+	118	<0.1	5.7	43.6	+
V:3	M	+	127	<0.1	7.1	75.0	+
V:4	M	−	145	0.5	2.8	ND	−
V:5	M	+	106	<0.1	6.8	64.3	+
V:7	F	+	94	<0.1	7.7	149.0	+
V:8	F	−	107	0.5	2.4	1.7	−
V:9	M	+	135	<0.1	6.3	65,6	+
V:12	F	ND	114	<0.1	6.7	184.0	+
V:13	F	−	145	1.9	2.0	2.6	−
V:14	M	+	113	<0.1	5.7	41.9	+
V:17	M	−	130	0.6	2.9	1.0	−
V:18	F	−	136	1.0	2.0	3.4	−
V:19	F	ND	153	0.7	2.1	4.0	−
V:20	M	ND	158	1.0	ND	3.3	−
V:22	F	+	121	<0.1	6.1	89.0	+
V:23	M	+	135	<0.1	6.4	139.0	+
V:24	M	ND	105	<0.1	ND	52.3	+
V:26	M	ND	120	<0.1	ND	108.0	+
V:27	M	ND	147	0.6	2.7	5.0	−
V:28	M	ND	145	0.3	3.1	8.0	−
V:30	F	ND	109	<0.1	4.1	120.0	+
V:31	M	ND	118	0.8	ND	3.8	−
V:32	M	ND	127	ND	3.4	7.0	−
V:33	F	+	119	0.1	4.3	18.5	+
V:35	M	ND	ND	<0.1	ND	69.0	+
V:36	F	+	124	<0.1	8.3	167.0	+
V:38	F	−	138	2,6	2.7	6.4	−
VI:1	F	ND	102	<0.1	7.5	279.0	+
VI:2	F	ND	133	1.22	2.2	30.0	−
VI:3	F	ND	114	1.87	2.6	ND	−
VI:4	M	+	123	<0.1	10.0	ND	+
VI:5	M	ND	149	0.53	3.3	ND	−
VI:6	F	ND	116	<0.1	5.9	116	+
VI:7	F	ND	109	<0.1	6.6	120	+
VI:8	M	ND	125	ND	4.6	134	+
VI:10	M	+	108	<0.1	5.8	286	+
VI:11	F	ND	115	ND	5.3	102	+
VI:14	F	ND	107	<0.1	8.8	ND	+

F, female; CDA III Hb, hemoglobin; LDH, lactate dehydrogenase; M, male; ND, no data.

Consistent with CDA III.

Normal range for males is 134-170 and for females 117-153.

Normal range 0.24-1.9.

Normal range <3.4, adjusted according to Nordic Reference Interval Project.

CDA III final diagnosis.