Table 1

Quantification of target cell killing dependent on CD20 organization

Profile of cappingPercent of conjugatesConjugates with killing
No capping 17.6% (21/119)* 42.9% (9/21) 
Capping 82.4% (98/119)* 68.4% (67/98) 
Localization of cap   
 Capping elsewhere 44.9% (44/98) 61.4% (27/44) 
 Capping on contact side 55.1% (54/98) 74.1% (40/54) 
Profile of cappingPercent of conjugatesConjugates with killing
No capping 17.6% (21/119)* 42.9% (9/21) 
Capping 82.4% (98/119)* 68.4% (67/98) 
Localization of cap   
 Capping elsewhere 44.9% (44/98) 61.4% (27/44) 
 Capping on contact side 55.1% (54/98) 74.1% (40/54) 
*

Percent of conjugates.

Percent of conjugates with CD20 capping.