Expression of Tribbles increased in specific AML karyotypes and FAB subtypes
Studies . | Trib1 (202241_at) . | Trib2 (202478_at) . | Trib3 (218145_at) . | |||
---|---|---|---|---|---|---|
Karyotype . | FAB . | Karyotype . | FAB . | Karyotype . | FAB . | |
Valk et al9 * | inv(16) or t(16; 16)† | M4† | NS | NS | t(8;21)† | M2† |
M5‡ | t(15;17)† | M3‡ | ||||
Gutierrez et al10 | inv(16) (p12; q13)† | M4Eo† | NS | NS | t(15;17)(q12;q21)† | M3† |
Verhaak et al11 | idt(16)† | M4‡ | NS | RAEB† | t(6;9)† | M2‡ |
inv(16)‡ | M5‡ | RAEB-t† | t(8;21)‡ | M3‡ | ||
t(6;9)† | t(15;17)‡ | |||||
Haferlach et al12 * | complex† | — | complex† | — | complex‡ | — |
t(8;21)† | inv(16) or t(16;16)† | t(15;17)† | ||||
Eppert et al13 | +13† | NS | inv(16)(p13;q22)† | M4Eo† | NS | NS |
inv(16)(p13;q22)† |
Studies . | Trib1 (202241_at) . | Trib2 (202478_at) . | Trib3 (218145_at) . | |||
---|---|---|---|---|---|---|
Karyotype . | FAB . | Karyotype . | FAB . | Karyotype . | FAB . | |
Valk et al9 * | inv(16) or t(16; 16)† | M4† | NS | NS | t(8;21)† | M2† |
M5‡ | t(15;17)† | M3‡ | ||||
Gutierrez et al10 | inv(16) (p12; q13)† | M4Eo† | NS | NS | t(15;17)(q12;q21)† | M3† |
Verhaak et al11 | idt(16)† | M4‡ | NS | RAEB† | t(6;9)† | M2‡ |
inv(16)‡ | M5‡ | RAEB-t† | t(8;21)‡ | M3‡ | ||
t(6;9)† | t(15;17)‡ | |||||
Haferlach et al12 * | complex† | — | complex† | — | complex‡ | — |
t(8;21)† | inv(16) or t(16;16)† | t(15;17)† | ||||
Eppert et al13 | +13† | NS | inv(16)(p13;q22)† | M4Eo† | NS | NS |
inv(16)(p13;q22)† |
AML samples with unknown karyotype or FAB subtype were excluded from statistical analysis provided by the LGA.
NS, no statistically significant increased expression found; –,unavailable data for statistical analysis.
AML samples with normal karyotype were not able to be included in the statistical analysis.
Statistically significant increased expression with adjusted P < .05 in Welch’s t test.
Statistically highly significant increased expression with adjusted P < .001 in Welch’s t test.