Multivariate analysis of clinicopathological parameters in de novo DLBCL treated with R-CHOP immunochemotherapy
| . | OS . | PFS . | ||||
|---|---|---|---|---|---|---|
| . | HR . | 95% CI . | P value . | HR . | 95% CI . | P value . |
| B symptoms | 1.36 | 0.95-1.94 | .0975 | 1.38 | 0.97-1.95 | .0712 |
| Tumor size ≥6 cm | 1.16 | 0.82-1.64 | .4154 | 1.13 | 0.81-1.58 | .4757 |
| IPI score >2 | 2.83 | 1.97-4.05 | <.0001 | 2.59 | 1.84-3.66 | <.0001 |
| ABC subtype | 1.56 | 1.08-2.24 | .0165 | 1.54 | 1.08-2.18 | .0157 |
| Negative CD30 IHC | 3.03 | 1.33-6.89 | .0082 | 2.89 | 1.35-6.20 | .0064 |
| TP53 mutation | 1.96 | 1.33-2.90 | .0007 | 1.84 | 1.26-2.69 | .0016 |
| . | OS . | PFS . | ||||
|---|---|---|---|---|---|---|
| . | HR . | 95% CI . | P value . | HR . | 95% CI . | P value . |
| B symptoms | 1.36 | 0.95-1.94 | .0975 | 1.38 | 0.97-1.95 | .0712 |
| Tumor size ≥6 cm | 1.16 | 0.82-1.64 | .4154 | 1.13 | 0.81-1.58 | .4757 |
| IPI score >2 | 2.83 | 1.97-4.05 | <.0001 | 2.59 | 1.84-3.66 | <.0001 |
| ABC subtype | 1.56 | 1.08-2.24 | .0165 | 1.54 | 1.08-2.18 | .0157 |
| Negative CD30 IHC | 3.03 | 1.33-6.89 | .0082 | 2.89 | 1.35-6.20 | .0064 |
| TP53 mutation | 1.96 | 1.33-2.90 | .0007 | 1.84 | 1.26-2.69 | .0016 |