Table 1 Characteristics of investigated... | American Society of Hematology

Table 1

Characteristics of investigated subjects

Subject	Sex	Blood group	Nucleotide change	Amino acid change	VWF:Ag, IU/dL	VWF:RCo, IU/dL	VWF:RCo/ VWF:Ag	FVIII:C, IU/dL	VWF:CB, IU/dL	Multimer pattern	VWD type^*
P6F1III1†	Female	O/O	c.2561G>A	p.Arg854Gln	73	114	1.56	59	Not tested	Normal	2N
P6F3II1§	Female	O/O	c.3853T>C	p.Ser1285Pro	16	3	0.19	27	8	Abnormal‡	1
P6F13II1§	Female	O/O	c.3920T>C	p.Leu1307Pro	16	7	0.44	33	6	Abnormal	2A
P6F12II1§	Female	O/O	c.4751A>G	p.Tyr1584Cys	48	36	0.75	64	52	Normal	1
P6F16II1§	Female	O/O	c.8078G>A	p.Cys2693Tyr	46	64	1.39	69	42	Normal	1

Subject	Sex	Blood group	Nucleotide change	Amino acid change	VWF:Ag, IU/dL	VWF:RCo, IU/dL	VWF:RCo/ VWF:Ag	FVIII:C, IU/dL	VWF:CB, IU/dL	Multimer pattern	VWD type^*
P6F1III1†	Female	O/O	c.2561G>A	p.Arg854Gln	73	114	1.56	59	Not tested	Normal	2N
P6F3II1§	Female	O/O	c.3853T>C	p.Ser1285Pro	16	3	0.19	27	8	Abnormal‡	1
P6F13II1§	Female	O/O	c.3920T>C	p.Leu1307Pro	16	7	0.44	33	6	Abnormal	2A
P6F12II1§	Female	O/O	c.4751A>G	p.Tyr1584Cys	48	36	0.75	64	52	Normal	1
P6F16II1§	Female	O/O	c.8078G>A	p.Cys2693Tyr	46	64	1.39	69	42	Normal	1

VWD type according to the 2006 classification.¹

Asymptomatic participants.

The multimer abnormality is minimal and fits classification of VWD type 1.³⁰

Characteristics of these 4 participants have been reported previously.²⁹