A summary of the clinical features of the lymphoma patients and the corresponding immunophenotypes
Individual . | Age of onset (y) . | Sites of involvement . | Diagnosis . | Immunophenotype . | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CD20 . | CD30 . | CD10 . | CD23 . | MIB1 . | IRF4/ MUM1 . | BCL2 . | BCL6 . | PAX5 . | OCT2 . | BOB1 . | LMP-1 . | ||||
III-1 | 35 | Mediastinal tumor | PMBCL stage IA | + | + | — | — | ∼50% | ± | ± | + | + | + | + | — |
III-2 | 46 | Mediastinal tumor; cervical, supraclavicular, and axillary lymph nodes | PMBCL stage IIIB | + | + | — | — | ∼50% | + | ± | + | + | + | + | — |
III-3 | 30 | Mediastinal tumor, minor liver involvement | PMBCL stage IVB | + | + | — | — | ∼50% | + | ± | + | + | + | + | — |
III-6 | 53 | Tumor between urinary bladder and uterus relapse: intestine and axillary lymph nodes | DLBCL stage IV | + | + | — | — | ∼97% | ++ | — | + | + | + | + | — |
Individual . | Age of onset (y) . | Sites of involvement . | Diagnosis . | Immunophenotype . | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CD20 . | CD30 . | CD10 . | CD23 . | MIB1 . | IRF4/ MUM1 . | BCL2 . | BCL6 . | PAX5 . | OCT2 . | BOB1 . | LMP-1 . | ||||
III-1 | 35 | Mediastinal tumor | PMBCL stage IA | + | + | — | — | ∼50% | ± | ± | + | + | + | + | — |
III-2 | 46 | Mediastinal tumor; cervical, supraclavicular, and axillary lymph nodes | PMBCL stage IIIB | + | + | — | — | ∼50% | + | ± | + | + | + | + | — |
III-3 | 30 | Mediastinal tumor, minor liver involvement | PMBCL stage IVB | + | + | — | — | ∼50% | + | ± | + | + | + | + | — |
III-6 | 53 | Tumor between urinary bladder and uterus relapse: intestine and axillary lymph nodes | DLBCL stage IV | + | + | — | — | ∼97% | ++ | — | + | + | + | + | — |
+, ++, positive staining; ±, moderate staining; −, negative staining.