Correlation between inflammatory cytokines in the different malaria clinical groups
. | IL-10 . | IL-6 . | GM-CSF . | TNF-α . | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
. | UM . | CM . | SMA . | UM . | CM . | SMA . | UM . | CM . | SMA . | UM . | CM . | SMA . |
IL-1β | r = 0.359 | r = 0.333 | r = 0.842 | r = 0.532 | r = 0.614 | r = 0.482 | r = 0.483 | r = 0.345 | r = 0.6276 | r = 0.524 | r = 0.384 | r = 0.535 |
P = .011 | P = .150 | P = .015 | P < .0001 | P = .004 | P = .015 | P = .004 | P = .137 | P = .0008 | P = .001 | P = .011 | P = .006 | |
TNF-α | r = 0.423 | r = 0.585 | r = 0.577 | r = 0.633 | r = 0.583 | r = 0.7347 | r = 0.638 | r = 0.5365 | r = 0.571 | |||
P = .003 | P = .007 | P = .001 | P < .0001 | P = .004 | P < .0001 | P < .0001 | P = .015 | P = .002 | ||||
GM-CSF | r = 0.808 | r = 0.453 | r = 0.4857 | r = 0.844 | r = 0.762 | r = 0.5667 | ||||||
P < .0001 | P = .045 | P = .009 | P < .0001 | P < .0001 | P = .002 | |||||||
IL-6 | r = 0.801 | r = 0.297 | r = 0.801 | |||||||||
P < .0001 | P = .179 | P < .0001 |
. | IL-10 . | IL-6 . | GM-CSF . | TNF-α . | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
. | UM . | CM . | SMA . | UM . | CM . | SMA . | UM . | CM . | SMA . | UM . | CM . | SMA . |
IL-1β | r = 0.359 | r = 0.333 | r = 0.842 | r = 0.532 | r = 0.614 | r = 0.482 | r = 0.483 | r = 0.345 | r = 0.6276 | r = 0.524 | r = 0.384 | r = 0.535 |
P = .011 | P = .150 | P = .015 | P < .0001 | P = .004 | P = .015 | P = .004 | P = .137 | P = .0008 | P = .001 | P = .011 | P = .006 | |
TNF-α | r = 0.423 | r = 0.585 | r = 0.577 | r = 0.633 | r = 0.583 | r = 0.7347 | r = 0.638 | r = 0.5365 | r = 0.571 | |||
P = .003 | P = .007 | P = .001 | P < .0001 | P = .004 | P < .0001 | P < .0001 | P = .015 | P = .002 | ||||
GM-CSF | r = 0.808 | r = 0.453 | r = 0.4857 | r = 0.844 | r = 0.762 | r = 0.5667 | ||||||
P < .0001 | P = .045 | P = .009 | P < .0001 | P < .0001 | P = .002 | |||||||
IL-6 | r = 0.801 | r = 0.297 | r = 0.801 | |||||||||
P < .0001 | P = .179 | P < .0001 |
r, nonparametric Spearman correlation coefficient (statistically significant if P < .01 according to the nonparametric Spearman r test).