Table 2

Inflammatory status of children in the different clinical groups

CCDCUMCMSMA
IL-1β, pg/mL 0.89 (0.22-3.81) 2.01 (0.48-2.90) 3.79* (1.45-5.81) 1.12 (0.36-2.44) 2.88*‡§ (1.94-5.97) 
IL-4, pg/mL 5.64 (1.61-25.04) 3.22* (1.61-3.76) 3.76* (1.88-5.64) 1.88*† (1.61-1.88) 3.22§ (1.61-3.76) 
IL-6, pg/mL 6.80 (2.99-19.82) 21.35* (9.82-73.67) 195.57*‡ (77.46-433.10) 75.30*† (21.53-140.27) 55.39*‡ (35.39-163.73) 
IL-8, pg/mL 392.59 (103.44-1127.22) 51.29* (21.50-418.11) 69.95* (30.79-141.90) 39.04* (13.47-153.80) 45.68* (27.78-227.82) 
IL-10, pg/mL 7.44 (3.70-13.45) 15.94* (5.31-37.19) 730.18*‡ (240.77-1900.77) 76.55*†‡ (45.80-489.80) 199.69*†‡ (112.37-397.60) 
TNF-α, pg/mL 1.80 (0.90-6.12) 1.80 (0.66-2.70) 4.60*‡ (2.70-11.68) 1.80 (0.66-3.29) 3.44 (0.98-6.57) 
GM-CSF, pg/mL 1.04 (0.93-2.87) 0.52* (0-0.93) 2.78*‡ (0.93-4.63) 0.93 (0.51-1.70) 1.24 (0.93-2.73) 
Ferritin, ng/mL 99.35 (55.07-154.10) 536.50* (144.10-755.30) 313.40* (176.70-509.80) 539.70*‡ (363.40-985.90) 583.20*† (472.10-985.90) 
Serum hepcidin, standardized peak intensity (m/z) −0.43 (−0.46 to −0.37) −0.44 (−0.48 to −0.36) 0.11*‡ (−0.38 to 1.037) −0.22*† (−0.43 to 0.62) −0.38 (−0.48 to 0.25) 
CCDCUMCMSMA
IL-1β, pg/mL 0.89 (0.22-3.81) 2.01 (0.48-2.90) 3.79* (1.45-5.81) 1.12 (0.36-2.44) 2.88*‡§ (1.94-5.97) 
IL-4, pg/mL 5.64 (1.61-25.04) 3.22* (1.61-3.76) 3.76* (1.88-5.64) 1.88*† (1.61-1.88) 3.22§ (1.61-3.76) 
IL-6, pg/mL 6.80 (2.99-19.82) 21.35* (9.82-73.67) 195.57*‡ (77.46-433.10) 75.30*† (21.53-140.27) 55.39*‡ (35.39-163.73) 
IL-8, pg/mL 392.59 (103.44-1127.22) 51.29* (21.50-418.11) 69.95* (30.79-141.90) 39.04* (13.47-153.80) 45.68* (27.78-227.82) 
IL-10, pg/mL 7.44 (3.70-13.45) 15.94* (5.31-37.19) 730.18*‡ (240.77-1900.77) 76.55*†‡ (45.80-489.80) 199.69*†‡ (112.37-397.60) 
TNF-α, pg/mL 1.80 (0.90-6.12) 1.80 (0.66-2.70) 4.60*‡ (2.70-11.68) 1.80 (0.66-3.29) 3.44 (0.98-6.57) 
GM-CSF, pg/mL 1.04 (0.93-2.87) 0.52* (0-0.93) 2.78*‡ (0.93-4.63) 0.93 (0.51-1.70) 1.24 (0.93-2.73) 
Ferritin, ng/mL 99.35 (55.07-154.10) 536.50* (144.10-755.30) 313.40* (176.70-509.80) 539.70*‡ (363.40-985.90) 583.20*† (472.10-985.90) 
Serum hepcidin, standardized peak intensity (m/z) −0.43 (−0.46 to −0.37) −0.44 (−0.48 to −0.36) 0.11*‡ (−0.38 to 1.037) −0.22*† (−0.43 to 0.62) −0.38 (−0.48 to 0.25) 

Level of serum inflammatory molecules shown as median (interquartile range).

*

Statistically different (P < .05) compared with CC.

Statistically different (P < .05) compared with UM.

Statistically different (P < .05) compared with DC.

§

Statistically different (P < .05) compared with CM.

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