Table 4. Comparison of recent ML-DS... | American Society of Hematology

Table 4.

Comparison of recent ML-DS trials

	Years	N	DNR, mg/m²	ARA-C, mg/m²	Etoposide, mg/m²	TRM, %	5-y OS, %	5-y EFS, %	Reference
ML-DS-06	2006-2015	170	240	27 400	450	2.9	89	87
AML-BFM 98	1998-2003	204	240	29 400	950	5.0	90	89	9
COG A2971	1999-2003	132	320	27 200	0*	2.3	84	79	12
Al-Ahmari	1990-2003	34	0	7 400	0	0	77	67	33
JPLSG D05	2008-2010	72	250	3 500	1350	1.4	88	83	15

	Years	N	DNR, mg/m²	ARA-C, mg/m²	Etoposide, mg/m²	TRM, %	5-y OS, %	5-y EFS, %	Reference
ML-DS-06	2006-2015	170	240	27 400	450	2.9	89	87
AML-BFM 98	1998-2003	204	240	29 400	950	5.0	90	89	9
COG A2971	1999-2003	132	320	27 200	0*	2.3	84	79	12
Al-Ahmari	1990-2003	34	0	7 400	0	0	77	67	33
JPLSG D05	2008-2010	72	250	3 500	1350	1.4	88	83	15

ARA-C, cytarabine; DNR, daunorubicin.

6-Thioguanine, 1600 mg/m²; l-asparaginase, 12 000 IU/m².