Adverse events per cycle for eligible AAML0431 patients
| Cycle . | n . | No. of patients with ANC recovery prior to starting next cycle . | Days to ANC recovery, median (range) . | ICU admission, % of patients . | Febrile neutropenia grade ≥3, % of patients . | Sterile site bacterial infection grade ≥3, % of patients . |
|---|---|---|---|---|---|---|
| Induction I | 204 | 89 | 30 (5-54) | 6.9 | 27 | 19.1 |
| Induction II | 199 | 94 | 37 (1-67) | 7.0 | 29.7 | 22.6 |
| Induction III | 195 | 115 | 28 (3-47) | 1.5 | 6.2 | 11.3 |
| Induction IV | 195 | 113 | 28 (3-47) | 2.1 | 5.6 | 8.7 |
| Intensification I | 192 | 89 | 33 (3-54) | 4.2 | 11.5 | 12.5 |
| Intensification II | 186 | 117 | 32 (7-63) | 1.1 | 12.4 | 8.1 |
| Cycle . | n . | No. of patients with ANC recovery prior to starting next cycle . | Days to ANC recovery, median (range) . | ICU admission, % of patients . | Febrile neutropenia grade ≥3, % of patients . | Sterile site bacterial infection grade ≥3, % of patients . |
|---|---|---|---|---|---|---|
| Induction I | 204 | 89 | 30 (5-54) | 6.9 | 27 | 19.1 |
| Induction II | 199 | 94 | 37 (1-67) | 7.0 | 29.7 | 22.6 |
| Induction III | 195 | 115 | 28 (3-47) | 1.5 | 6.2 | 11.3 |
| Induction IV | 195 | 113 | 28 (3-47) | 2.1 | 5.6 | 8.7 |
| Intensification I | 192 | 89 | 33 (3-54) | 4.2 | 11.5 | 12.5 |
| Intensification II | 186 | 117 | 32 (7-63) | 1.1 | 12.4 | 8.1 |
ICU, intensive care unit.