Patient responses to DLI
| UPN . | Disease status at alloTCD-HSCT . | Disease status pre-DLI 1 . | No. of DLI received . | Maximum WT1-CTL response post-DLI, absolute no./μL PB . | Best response after DLI . | Maximum WT1 expression* . | WT1 expression pre-alloTCD-HSCT* . | WT1 expression post-DLI* . |
|---|---|---|---|---|---|---|---|---|
| 1 | VGPR | VGPR | 2 | 92.14 | VGPR | + | Focal | ND |
| 2 | CR | CR | 3 | 6.66 | CR | + | + | Negative |
| 3 | CR | CR | 4 | 5.05 | CR | Focal | ND | Focal |
| 4 | CR | POD | 2 | 47.81 | CR | Focal | Focal | Focal |
| 5 | PR | CR | 5 | 14.02 | PR | ++++ | ++++ | ++++ |
| 6 | PR | VGPR | 2 | 94.94 | PR | ++++ | ++++ | + |
| 7 | CR | POD | 2 | 72.5 | CR | Focal | Focal | Focal |
| 8 | PR | VGPR | 6 | 77.5 | VGPR | Focal | Focal | Negative |
| 9 | VGPR | CR | 3 | 40.84 | CR | Focal | Negative | Negative |
| 10 | VGPR | POD | 6 | 21.55 | PR | ++ | Focal | Negative |
| UPN . | Disease status at alloTCD-HSCT . | Disease status pre-DLI 1 . | No. of DLI received . | Maximum WT1-CTL response post-DLI, absolute no./μL PB . | Best response after DLI . | Maximum WT1 expression* . | WT1 expression pre-alloTCD-HSCT* . | WT1 expression post-DLI* . |
|---|---|---|---|---|---|---|---|---|
| 1 | VGPR | VGPR | 2 | 92.14 | VGPR | + | Focal | ND |
| 2 | CR | CR | 3 | 6.66 | CR | + | + | Negative |
| 3 | CR | CR | 4 | 5.05 | CR | Focal | ND | Focal |
| 4 | CR | POD | 2 | 47.81 | CR | Focal | Focal | Focal |
| 5 | PR | CR | 5 | 14.02 | PR | ++++ | ++++ | ++++ |
| 6 | PR | VGPR | 2 | 94.94 | PR | ++++ | ++++ | + |
| 7 | CR | POD | 2 | 72.5 | CR | Focal | Focal | Focal |
| 8 | PR | VGPR | 6 | 77.5 | VGPR | Focal | Focal | Negative |
| 9 | VGPR | CR | 3 | 40.84 | CR | Focal | Negative | Negative |
| 10 | VGPR | POD | 6 | 21.55 | PR | ++ | Focal | Negative |
UPN indicates unidentified patient number; alloTCD-HSCT, allogeneic T cell–depleted hematopoietic stem cell transplantation; DLI, donor lymphocyte infusion; PB, peripheral blood; VGPR, very good partial response; CR, complete remission; POD, progression of disease; PR, partial response; and ND, not done.
WT1 expression determined by immunohistochemical analysis.