Operating characteristics of the assays at the most northwest point on the ROC curve
| Assay . | Cutoff . | Sensitivity (95% CI) . | Specificity (95% CI) . |
|---|---|---|---|
| Polyspecific ELISA | 1.72 OD | 0.76 (0.53-0.92) | 0.78 (0.62-0.90) |
| IgG-specific ELISA | 1.70 OD | 0.67 (0.43-0.85) | 0.76 (0.59-0.88) |
| KKO-I | 66% | 0.90 (0.68-0.99) | 0.92 (0.78-0.98) |
| DT40-luc | 1.6-fold basal | 0.81 (0.58-0.95) | 0.95 (0.82-0.99) |
| Combinatorial | KKO-I ≥75% or DT40-luc ≥ 2-fold basal | 0.95 (0.74-1.00) | 0.94 (0.80-0.99) |
| Assay . | Cutoff . | Sensitivity (95% CI) . | Specificity (95% CI) . |
|---|---|---|---|
| Polyspecific ELISA | 1.72 OD | 0.76 (0.53-0.92) | 0.78 (0.62-0.90) |
| IgG-specific ELISA | 1.70 OD | 0.67 (0.43-0.85) | 0.76 (0.59-0.88) |
| KKO-I | 66% | 0.90 (0.68-0.99) | 0.92 (0.78-0.98) |
| DT40-luc | 1.6-fold basal | 0.81 (0.58-0.95) | 0.95 (0.82-0.99) |
| Combinatorial | KKO-I ≥75% or DT40-luc ≥ 2-fold basal | 0.95 (0.74-1.00) | 0.94 (0.80-0.99) |