Basic laboratory evaluation of pregnant women with isolated thrombocytopenia
Complete blood count and reticulocyte count |
Peripheral blood film |
Liver function tests |
Thyroid function tests |
Quantitative immunoglobulin level measurement |
Direct antiglobulin test |
Antiphospholipid antibodies |
ANA |
H pylori |
HIV |
HCV |
HBV |
VWD type IIB testing* |
Complete blood count and reticulocyte count |
Peripheral blood film |
Liver function tests |
Thyroid function tests |
Quantitative immunoglobulin level measurement |
Direct antiglobulin test |
Antiphospholipid antibodies |
ANA |
H pylori |
HIV |
HCV |
HBV |
VWD type IIB testing* |
ANA indicates antinuclear antibody.
Laboratory investigation of type IIB VWD may be indicated if there is a history of bleeding or family history of thrombocytopenia or if therapy for ITP is ineffective. First-tier tests will include VWF activity (VWF:RCo) and antigen, ristocetin-induced platelet aggregation, and multimeric analysis of VWF.