Table 3

Basic laboratory evaluation of pregnant women with isolated thrombocytopenia

Complete blood count and reticulocyte count 
Peripheral blood film 
Liver function tests 
Thyroid function tests 
Quantitative immunoglobulin level measurement 
Direct antiglobulin test 
Antiphospholipid antibodies 
ANA 
H pylori 
HIV 
HCV 
HBV 
VWD type IIB testing* 
Complete blood count and reticulocyte count 
Peripheral blood film 
Liver function tests 
Thyroid function tests 
Quantitative immunoglobulin level measurement 
Direct antiglobulin test 
Antiphospholipid antibodies 
ANA 
H pylori 
HIV 
HCV 
HBV 
VWD type IIB testing* 

ANA indicates antinuclear antibody.

*

Laboratory investigation of type IIB VWD may be indicated if there is a history of bleeding or family history of thrombocytopenia or if therapy for ITP is ineffective. First-tier tests will include VWF activity (VWF:RCo) and antigen, ristocetin-induced platelet aggregation, and multimeric analysis of VWF.

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