Ikaros binding to differentially expressed genes in pre-B cells
| . | All . | Up-regulated . | Down-regulated . |
|---|---|---|---|
| Ikaros-responsive genes at 2 h | 79 | 28 | 51 |
| Ikaros binding observed | 65 (82.3%) | 22 (78.6%) | 43 (84.3%) |
| Ikaros binding expected | 28 | 10 | 18 |
| P value | 9.90 × 10−19 | 4.55 × 10−7 | 5.08 × 10−14 |
| Odds ratio | 8.55 | 6.75 | 9.90 |
| Ikaros-responsive genes at 6 h | 401 | 159 | 242 |
| Ikaros binding observed | 286 (71.3%) | 112 (70.4%) | 174 (71.9%) |
| Ikaros binding expected | 141 | 56 | 85 |
| P value | 5.88 × 10−51 | 2.35 × 10−20 | 2.39 × 10−32 |
| Odds ratio | 4.58 | 4.39 | 4.71 |
| Ikaros-responsive genes at 48 h | 4471 | 1982 | 2486 |
| Ikaros binding observed | 2497 (55.8%) | 1195 (60.3%) | 1302 (41.5%) |
| Ikaros binding expected | 1573 | 697 | 875 |
| P value | 2.16 × 10−246 | 1.43 × 10−131 | 7.52 × 10−82 |
| Odds ratio | 2.33 | 2.80 | 1.398 |
| . | All . | Up-regulated . | Down-regulated . |
|---|---|---|---|
| Ikaros-responsive genes at 2 h | 79 | 28 | 51 |
| Ikaros binding observed | 65 (82.3%) | 22 (78.6%) | 43 (84.3%) |
| Ikaros binding expected | 28 | 10 | 18 |
| P value | 9.90 × 10−19 | 4.55 × 10−7 | 5.08 × 10−14 |
| Odds ratio | 8.55 | 6.75 | 9.90 |
| Ikaros-responsive genes at 6 h | 401 | 159 | 242 |
| Ikaros binding observed | 286 (71.3%) | 112 (70.4%) | 174 (71.9%) |
| Ikaros binding expected | 141 | 56 | 85 |
| P value | 5.88 × 10−51 | 2.35 × 10−20 | 2.39 × 10−32 |
| Odds ratio | 4.58 | 4.39 | 4.71 |
| Ikaros-responsive genes at 48 h | 4471 | 1982 | 2486 |
| Ikaros binding observed | 2497 (55.8%) | 1195 (60.3%) | 1302 (41.5%) |
| Ikaros binding expected | 1573 | 697 | 875 |
| P value | 2.16 × 10−246 | 1.43 × 10−131 | 7.52 × 10−82 |
| Odds ratio | 2.33 | 2.80 | 1.398 |