Incremental values of the molecular predictors when added to the clinical factors
| Risk factor . | RCHOP . | CHOP . | ||||
|---|---|---|---|---|---|---|
| C-statistic . | Difference in C (95% CI) . | IDI . | C-statistic . | Difference in C (95% CI) . | IDI . | |
| Clinical factors | 0.739 | 0.721 | ||||
| Clinical factors + 6-gene predictor | 0.752 (0.600)* | 0.013 (−0.021, 0.047) | 0.001 (−0.008, 0.049) | 0.724 (0.678)* | 0.002 (−0.021, 0.026) | 0.022 (−0.006, 0.080) |
| Clinical factors + 3-component signature | 0.771 (0.717)* | 0.031 (−0.026, 0.089) | 0.076 (0.013, 0.167) | |||
| Clinical factors + 2-gene model | 0.739 (0.619)* | 0.018 (−0.016, 0.052) | 0.037 (−0.002, 0.098) | |||
| Risk factor . | RCHOP . | CHOP . | ||||
|---|---|---|---|---|---|---|
| C-statistic . | Difference in C (95% CI) . | IDI . | C-statistic . | Difference in C (95% CI) . | IDI . | |
| Clinical factors | 0.739 | 0.721 | ||||
| Clinical factors + 6-gene predictor | 0.752 (0.600)* | 0.013 (−0.021, 0.047) | 0.001 (−0.008, 0.049) | 0.724 (0.678)* | 0.002 (−0.021, 0.026) | 0.022 (−0.006, 0.080) |
| Clinical factors + 3-component signature | 0.771 (0.717)* | 0.031 (−0.026, 0.089) | 0.076 (0.013, 0.167) | |||
| Clinical factors + 2-gene model | 0.739 (0.619)* | 0.018 (−0.016, 0.052) | 0.037 (−0.002, 0.098) | |||
C-statistic when molecular predictor was used alone.