Table 4

Poisson regression evaluating the influence of any G-CSF prophylaxis (N = 116) or no discharge policy (N = 563)

InfectionNRoutine G-CSF prophylaxis
No discharge policy
IRR (95% CI)PAdjusted IRR (95% CI)Adjusted P*IRR (95% CI)PAdjusted IRR (95% CI)Adjusted P*
Any sterile-site bacterial infection 612 0.82 (0.70-0.96) .016 0.79 (0.67-0.92) .004 0.91 (0.82-1.01) .083 0.91 (0.82-1.01) .084 
Gram-positive sterile-site bacterial infection 512 0.87 (0.72-1.06) .167 0.83 (0.68-1.02) .082 0.96 (0.84-1.09) .500 0.95 (0.83-1.10) .502 
Gram-negative sterile-site bacterial infection 78 0.89 (0.46-1.73) .732 0.69 (0.32-1.52) .362 1.01 (0.64-1.58) .974 1.07 (0.65-1.77) .778 
C difficile infection 123 0.52 (0.29-0.94) .031 0.46 (0.25-0.84) .012 1.88 (1.30-2.72) <.001 1.96 (1.34-2.87) <.001 
Sterile-site fungal infection 49 1.08 (0.49-2.41) .844 1.13 (0.50-2.53) .772 0.56 (0.32-0.99) .045 0.68 (0.37-1.23) .198 
InfectionNRoutine G-CSF prophylaxis
No discharge policy
IRR (95% CI)PAdjusted IRR (95% CI)Adjusted P*IRR (95% CI)PAdjusted IRR (95% CI)Adjusted P*
Any sterile-site bacterial infection 612 0.82 (0.70-0.96) .016 0.79 (0.67-0.92) .004 0.91 (0.82-1.01) .083 0.91 (0.82-1.01) .084 
Gram-positive sterile-site bacterial infection 512 0.87 (0.72-1.06) .167 0.83 (0.68-1.02) .082 0.96 (0.84-1.09) .500 0.95 (0.83-1.10) .502 
Gram-negative sterile-site bacterial infection 78 0.89 (0.46-1.73) .732 0.69 (0.32-1.52) .362 1.01 (0.64-1.58) .974 1.07 (0.65-1.77) .778 
C difficile infection 123 0.52 (0.29-0.94) .031 0.46 (0.25-0.84) .012 1.88 (1.30-2.72) <.001 1.96 (1.34-2.87) <.001 
Sterile-site fungal infection 49 1.08 (0.49-2.41) .844 1.13 (0.50-2.53) .772 0.56 (0.32-0.99) .045 0.68 (0.37-1.23) .198 

No discharge indicates institutions that never discharge patients prior to count recovery vs those who always or sometimes discharge patients early.

*

Analysis adjusted for age, race, and weight group.

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