Poisson regression evaluating the influence of any G-CSF prophylaxis (N = 116) or no discharge policy (N = 563)
Infection . | N . | Routine G-CSF prophylaxis . | No discharge policy . | ||||||
---|---|---|---|---|---|---|---|---|---|
IRR (95% CI) . | P . | Adjusted IRR (95% CI) . | Adjusted P* . | IRR (95% CI) . | P . | Adjusted IRR (95% CI) . | Adjusted P* . | ||
Any sterile-site bacterial infection | 612 | 0.82 (0.70-0.96) | .016 | 0.79 (0.67-0.92) | .004 | 0.91 (0.82-1.01) | .083 | 0.91 (0.82-1.01) | .084 |
Gram-positive sterile-site bacterial infection | 512 | 0.87 (0.72-1.06) | .167 | 0.83 (0.68-1.02) | .082 | 0.96 (0.84-1.09) | .500 | 0.95 (0.83-1.10) | .502 |
Gram-negative sterile-site bacterial infection | 78 | 0.89 (0.46-1.73) | .732 | 0.69 (0.32-1.52) | .362 | 1.01 (0.64-1.58) | .974 | 1.07 (0.65-1.77) | .778 |
C difficile infection | 123 | 0.52 (0.29-0.94) | .031 | 0.46 (0.25-0.84) | .012 | 1.88 (1.30-2.72) | <.001 | 1.96 (1.34-2.87) | <.001 |
Sterile-site fungal infection | 49 | 1.08 (0.49-2.41) | .844 | 1.13 (0.50-2.53) | .772 | 0.56 (0.32-0.99) | .045 | 0.68 (0.37-1.23) | .198 |
Infection . | N . | Routine G-CSF prophylaxis . | No discharge policy . | ||||||
---|---|---|---|---|---|---|---|---|---|
IRR (95% CI) . | P . | Adjusted IRR (95% CI) . | Adjusted P* . | IRR (95% CI) . | P . | Adjusted IRR (95% CI) . | Adjusted P* . | ||
Any sterile-site bacterial infection | 612 | 0.82 (0.70-0.96) | .016 | 0.79 (0.67-0.92) | .004 | 0.91 (0.82-1.01) | .083 | 0.91 (0.82-1.01) | .084 |
Gram-positive sterile-site bacterial infection | 512 | 0.87 (0.72-1.06) | .167 | 0.83 (0.68-1.02) | .082 | 0.96 (0.84-1.09) | .500 | 0.95 (0.83-1.10) | .502 |
Gram-negative sterile-site bacterial infection | 78 | 0.89 (0.46-1.73) | .732 | 0.69 (0.32-1.52) | .362 | 1.01 (0.64-1.58) | .974 | 1.07 (0.65-1.77) | .778 |
C difficile infection | 123 | 0.52 (0.29-0.94) | .031 | 0.46 (0.25-0.84) | .012 | 1.88 (1.30-2.72) | <.001 | 1.96 (1.34-2.87) | <.001 |
Sterile-site fungal infection | 49 | 1.08 (0.49-2.41) | .844 | 1.13 (0.50-2.53) | .772 | 0.56 (0.32-0.99) | .045 | 0.68 (0.37-1.23) | .198 |
No discharge indicates institutions that never discharge patients prior to count recovery vs those who always or sometimes discharge patients early.
Analysis adjusted for age, race, and weight group.