Poisson regression evaluating the influence of any antibacterial prophylaxis (N = 115) or penicillin/vancomycin prophylaxis (N = 70)
| Infection . | N . | Any antibacterial prophylaxis . | Penicillin or vancomycin prophylaxis . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| IRR (95% CI) . | P . | Adjusted IRR* (95% CI) . | Adjusted P* . | IRR . | P . | Adjusted IRR* (95% CI) . | Adjusted P* . | ||
| Any sterile-site bacterial infection | 612 | 0.84 (0.71-0.98) | .028 | 0.85 (0.72-1.01) | .058 | 0.87 (0.72-1.05) | .150 | 0.92 (0.75-1.12) | .398 |
| Gram-positive sterile-site bacterial infection | 512 | 0.72 (0.58-0.90) | .004 | 0.71 (0.57-0.90) | .004 | 0.73 (0.56-0.95) | .021 | 0.76 (0.58-1.01) | .054 |
| Gram-negative sterile-site bacterial infection | 78 | 1.39 (0.78-2.47) | .258 | 1.39 (0.75-2.60) | .297 | 1.03 (0.48-2.23) | .940 | 1.07 (0.46-2.48) | .872 |
| C difficile infection | 123 | 0.77 (0.46-1.30) | .330 | 0.65 (0.38-1.13) | .126 | 1.09 (0.63-1.88) | .769 | 0.88 (0.48-1.59) | .674 |
| Sterile-site fungal infection | 49 | 1.07 (0.49-2.38) | .860 | 1.11 (0.47-2.63) | .812 | 1.47 (0.63-3.43) | .378 | 1.50 (0.59-3.81) | .399 |
| Infection . | N . | Any antibacterial prophylaxis . | Penicillin or vancomycin prophylaxis . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| IRR (95% CI) . | P . | Adjusted IRR* (95% CI) . | Adjusted P* . | IRR . | P . | Adjusted IRR* (95% CI) . | Adjusted P* . | ||
| Any sterile-site bacterial infection | 612 | 0.84 (0.71-0.98) | .028 | 0.85 (0.72-1.01) | .058 | 0.87 (0.72-1.05) | .150 | 0.92 (0.75-1.12) | .398 |
| Gram-positive sterile-site bacterial infection | 512 | 0.72 (0.58-0.90) | .004 | 0.71 (0.57-0.90) | .004 | 0.73 (0.56-0.95) | .021 | 0.76 (0.58-1.01) | .054 |
| Gram-negative sterile-site bacterial infection | 78 | 1.39 (0.78-2.47) | .258 | 1.39 (0.75-2.60) | .297 | 1.03 (0.48-2.23) | .940 | 1.07 (0.46-2.48) | .872 |
| C difficile infection | 123 | 0.77 (0.46-1.30) | .330 | 0.65 (0.38-1.13) | .126 | 1.09 (0.63-1.88) | .769 | 0.88 (0.48-1.59) | .674 |
| Sterile-site fungal infection | 49 | 1.07 (0.49-2.38) | .860 | 1.11 (0.47-2.63) | .812 | 1.47 (0.63-3.43) | .378 | 1.50 (0.59-3.81) | .399 |
Analysis adjusted for age, race, and weight group.