Table 1 Characteristics in children with... | American Society of Hematology

Table 1

Characteristics in children with de novo AML enrolled on AAML0531 and treated at institutions who responded to the survey

Characteristic	All patients, N = 897		Antibacterial prophylaxis, N = 115		Antifungal prophylaxis, N = 730		No discharge,* N = 573
Characteristic	N	%	N	%	N	%	N	%
Gender
Female	455	51	72	63	370	51	277	48
Male	442	49	43	37	360	49	296	52
Age, y
0-1	184	21	23	20	152	21	125	22
2-16	624	70	83	72	507	69	390	68
≥17	89	10	9	8	71	10	58	10
Race
White	642	81	83	86	512	80	402	81
Asian	45	6	2	2	34	5	26	5
African American	105	13	10	10	88	14	67	13
Other	5	1	1	1	3	1	3	1
Unknown	100		19		93		75
Weight group†
Underweight	64	8	6	6	54	8	32	7
Middleweight	584	74	79	78	471	73	363	73
Overweight	139	18	16	16	117	18	100	20
Unknown	110		14		88		78
FAB classification
M0	18	2	2	2	18	3	16	3
M1	93	12	6	6	70	11	60	12
M2	180	24	30	32	142	23	104	21
M4	184	24	25	27	149	24	116	24
M5	167	22	24	26	135	22	116	24
M6	13	2	1	1	9	1	6	1
M7	42	6	3	3	39	6	29	6
AML NOS	48	6	2	2	43	7	29	6
Other/	12	2	1	1	10	2	9	2
Unknown	140		21		115		88
Cytogenetic group†
Favorable	210	24	24	22	161	23	121	22
Standard	621	72	84	76	512	73	411	75
Unfavorable	31	4	3	3	26	4	19	3
Unknown	35		4		31		22

Characteristic	All patients, N = 897		Antibacterial prophylaxis, N = 115		Antifungal prophylaxis, N = 730		No discharge,* N = 573
Characteristic	N	%	N	%	N	%	N	%
Gender
Female	455	51	72	63	370	51	277	48
Male	442	49	43	37	360	49	296	52
Age, y
0-1	184	21	23	20	152	21	125	22
2-16	624	70	83	72	507	69	390	68
≥17	89	10	9	8	71	10	58	10
Race
White	642	81	83	86	512	80	402	81
Asian	45	6	2	2	34	5	26	5
African American	105	13	10	10	88	14	67	13
Other	5	1	1	1	3	1	3	1
Unknown	100		19		93		75
Weight group†
Underweight	64	8	6	6	54	8	32	7
Middleweight	584	74	79	78	471	73	363	73
Overweight	139	18	16	16	117	18	100	20
Unknown	110		14		88		78
FAB classification
M0	18	2	2	2	18	3	16	3
M1	93	12	6	6	70	11	60	12
M2	180	24	30	32	142	23	104	21
M4	184	24	25	27	149	24	116	24
M5	167	22	24	26	135	22	116	24
M6	13	2	1	1	9	1	6	1
M7	42	6	3	3	39	6	29	6
AML NOS	48	6	2	2	43	7	29	6
Other/	12	2	1	1	10	2	9	2
Unknown	140		21		115		88
Cytogenetic group†
Favorable	210	24	24	22	161	23	121	22
Standard	621	72	84	76	512	73	411	75
Unfavorable	31	4	3	3	26	4	19	3
Unknown	35		4		31		22

FAB, French-American-British; NOS, not otherwise specified.

No discharge indicates institutions that never discharge patients prior to count recovery vs those who always or sometimes discharge patients early.

See Materials for details of weight and cytogenetic- risk groups.