Table 1

Identification of potential downstream target genes of SOX4 in ATL

NameGene symbolFold changeProbe set
MARCKS-like protein 1 (MARCKS-related protein) MARCKSL1 (MRP) 4.5 200644_at 
Aquaporin 3 AQP3 4.3 203747_at 
Chondroitin sulfate N-acetylgalactosaminyltransferase 2 CSGALNACT2 3.8 218871_x_at 
Transmembrane emp24 protein transport domain containing 9 TMED9 3.3 208757_at 
Dedicator of cytokinesis 11 DOCK11 3.3 238356_at 
Poly (ADP-ribose) polymerase family, member 6 PARP6 3.3 234710_s_at 
Wolf-Hirschhorn syndrome candidate 2 WHSC2 3.2 203112_s_at 
AE-binding protein 2 AEBP2 3.2 225889_at 
SEC16 homolog B (S cerevisiaeSEC16B 3.0 1564423_a_at 
Kelch-like 23 (DrosophilaKLHL23 3.0 213610_s_at 
Superoxide dismutase 2, mitochondrial SOD2 2.9 221477_s_at 
Heparan sulfate 2-O-sulfotransferase 1 HS2ST1 2.9 203285_s_at 
Armadillo repeat containing, X-linked 4 ARMCX4 2.9 227444_at 
Solute carrier family 4, sodium bicarbonate cotransporter, member 7 SLC4A7 2.8 209884_s_at 
RAP1 interacting factor homolog (yeast) RIF1 2.8 214700_x_at 
ArfGAP with FG repeats 2 AGFG2 2.7 222126_at 
AT-rich interactive domain 1B (SWI1-like) ARID1B 2.7 225181_at 
Calpain 1, (μ/I) large subunit CAPN1 2.7 200752_s_at 
Ligand of numb-protein × 2 LNX2 2.7 227569_at 
Family with sequence similarity 189, member B FAM189B 2.6 203550_s_at 
Major histocompatibility complex, class II, DQ β 1 HLA-DQB1 2.6 211656_x_at 
Tax1 (human T-cell leukemia virus type I) binding protein 3 TAX1BP3 2.6 215464_s_at 
Mitogen-activated protein kinase kinase kinase kinase 5 (germinal center kinase related) MAP4K5 (GCKR) 2.6 203552_at 
RAB6A, member RAS oncogene family RAB6A 2.6 201048_x_at 
Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 MLLT4 2.6 224685_at 
Homeobox B7 HOXB7 2.6 204779_s_at 
5-azacytidine induced 2 (NAK-associated protein 1) AZI2 (NAP1) 2.6 227904_at 
Histone deacetylase 8 HDAC8 2.6 223345_at 
Hemoglobin, ε 1 HBE1 2.5 205919_at 
fem-1 homolog c (C. elegans) FEM1C 2.5 213341_at 
COMM domain containing 5 COMMD5 2.5 224387_at 
Solute carrier family 44, member 2 SLC44A2 2.5 224609_at 
Matrin 3 MATR3 2.4 242260_at 
Tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) TFPI 2.4 210664_s_at 
Protein phosphatase 1, catalytic subunit, β isozyme PPP1CB 2.4 201408_at 
β-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) B3GAT3 2.4 203452_at 
Pyroglutamyl-peptidase I PGPEP1 2.4 219891_at 
ADP-ribosylation factor–like 1 ARL1 2.4 201657_at 
Taxilin γ TXLNG 2.4 219969_at 
Acyl-CoA synthetase family member 3 ACSF3 2.4 1556552_a_at 
Retinol dehydrogenase 11 (all-trans/9-cis/11-cis) RDH11 2.4 217776_at 
Ataxin 7–like 1 ATXN7L1 2.4 227732_at 
Adaptor-related protein complex 3, δ 1 subunit AP3D1 2.4 210974_s_at 
Nucleoporin 160 kDa NUP160 2.4 214963_at 
Discs, large (Drosophila) homolog-associated protein 4 DLGAP4 2.4 202572_s_at 
Heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 HS3ST3B1 2.4 1561908_a_at 
AP2-associated kinase 1 AAK1 2.3 205434_s_at 
Insulin-induced gene 1 INSIG1 2.3 201625_s_at 
Calponin 2 CNN2 2.3 201605_x_at 
Polymerase (RNA) mitochondrial (DNA directed) POLRMT 2.3 203783_x_at 
NameGene symbolFold changeProbe set
MARCKS-like protein 1 (MARCKS-related protein) MARCKSL1 (MRP) 4.5 200644_at 
Aquaporin 3 AQP3 4.3 203747_at 
Chondroitin sulfate N-acetylgalactosaminyltransferase 2 CSGALNACT2 3.8 218871_x_at 
Transmembrane emp24 protein transport domain containing 9 TMED9 3.3 208757_at 
Dedicator of cytokinesis 11 DOCK11 3.3 238356_at 
Poly (ADP-ribose) polymerase family, member 6 PARP6 3.3 234710_s_at 
Wolf-Hirschhorn syndrome candidate 2 WHSC2 3.2 203112_s_at 
AE-binding protein 2 AEBP2 3.2 225889_at 
SEC16 homolog B (S cerevisiaeSEC16B 3.0 1564423_a_at 
Kelch-like 23 (DrosophilaKLHL23 3.0 213610_s_at 
Superoxide dismutase 2, mitochondrial SOD2 2.9 221477_s_at 
Heparan sulfate 2-O-sulfotransferase 1 HS2ST1 2.9 203285_s_at 
Armadillo repeat containing, X-linked 4 ARMCX4 2.9 227444_at 
Solute carrier family 4, sodium bicarbonate cotransporter, member 7 SLC4A7 2.8 209884_s_at 
RAP1 interacting factor homolog (yeast) RIF1 2.8 214700_x_at 
ArfGAP with FG repeats 2 AGFG2 2.7 222126_at 
AT-rich interactive domain 1B (SWI1-like) ARID1B 2.7 225181_at 
Calpain 1, (μ/I) large subunit CAPN1 2.7 200752_s_at 
Ligand of numb-protein × 2 LNX2 2.7 227569_at 
Family with sequence similarity 189, member B FAM189B 2.6 203550_s_at 
Major histocompatibility complex, class II, DQ β 1 HLA-DQB1 2.6 211656_x_at 
Tax1 (human T-cell leukemia virus type I) binding protein 3 TAX1BP3 2.6 215464_s_at 
Mitogen-activated protein kinase kinase kinase kinase 5 (germinal center kinase related) MAP4K5 (GCKR) 2.6 203552_at 
RAB6A, member RAS oncogene family RAB6A 2.6 201048_x_at 
Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 MLLT4 2.6 224685_at 
Homeobox B7 HOXB7 2.6 204779_s_at 
5-azacytidine induced 2 (NAK-associated protein 1) AZI2 (NAP1) 2.6 227904_at 
Histone deacetylase 8 HDAC8 2.6 223345_at 
Hemoglobin, ε 1 HBE1 2.5 205919_at 
fem-1 homolog c (C. elegans) FEM1C 2.5 213341_at 
COMM domain containing 5 COMMD5 2.5 224387_at 
Solute carrier family 44, member 2 SLC44A2 2.5 224609_at 
Matrin 3 MATR3 2.4 242260_at 
Tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) TFPI 2.4 210664_s_at 
Protein phosphatase 1, catalytic subunit, β isozyme PPP1CB 2.4 201408_at 
β-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) B3GAT3 2.4 203452_at 
Pyroglutamyl-peptidase I PGPEP1 2.4 219891_at 
ADP-ribosylation factor–like 1 ARL1 2.4 201657_at 
Taxilin γ TXLNG 2.4 219969_at 
Acyl-CoA synthetase family member 3 ACSF3 2.4 1556552_a_at 
Retinol dehydrogenase 11 (all-trans/9-cis/11-cis) RDH11 2.4 217776_at 
Ataxin 7–like 1 ATXN7L1 2.4 227732_at 
Adaptor-related protein complex 3, δ 1 subunit AP3D1 2.4 210974_s_at 
Nucleoporin 160 kDa NUP160 2.4 214963_at 
Discs, large (Drosophila) homolog-associated protein 4 DLGAP4 2.4 202572_s_at 
Heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 HS3ST3B1 2.4 1561908_a_at 
AP2-associated kinase 1 AAK1 2.3 205434_s_at 
Insulin-induced gene 1 INSIG1 2.3 201625_s_at 
Calponin 2 CNN2 2.3 201605_x_at 
Polymerase (RNA) mitochondrial (DNA directed) POLRMT 2.3 203783_x_at 

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