Table 1

Patient characteristics

Present study (N = 60)Previous study (N = 28)
Median age, y (range) 57.5 (40-66) 56 (33-64) 
Sex ratio 49 male/11 female 23 male/5 female 
Stage 3/4, no. (%) 60/60 (100) 28/28 (100) 
B symptoms, no. (%) 15/60 (25) 14/28 (50) 
PS > 1, no. (%) 4/60 (7) 0/28 (0) 
LDH > N, no. (%) 23/60 (38) 12/28 (41) 
β2-microglobulin > N, no. (%) 18/38 (47) 14/28 (50) 
Median albumin, g/L (range) 41 (26-60) NA 
Bone marrow involvement, no. (%) 51/60 (85) 25/28 (89) 
Leukemic phase, no. (%) 29/60 (48) 14/28 (50) 
Gastrointestinal involvement, no. (%) 15/29 (52) 11/23 (48) 
MIPI, no. (%)   
    Low 33/60 (55) NA 
    Intermediate 19/60 (32) NA 
    High 8/60 (13) NA 
Present study (N = 60)Previous study (N = 28)
Median age, y (range) 57.5 (40-66) 56 (33-64) 
Sex ratio 49 male/11 female 23 male/5 female 
Stage 3/4, no. (%) 60/60 (100) 28/28 (100) 
B symptoms, no. (%) 15/60 (25) 14/28 (50) 
PS > 1, no. (%) 4/60 (7) 0/28 (0) 
LDH > N, no. (%) 23/60 (38) 12/28 (41) 
β2-microglobulin > N, no. (%) 18/38 (47) 14/28 (50) 
Median albumin, g/L (range) 41 (26-60) NA 
Bone marrow involvement, no. (%) 51/60 (85) 25/28 (89) 
Leukemic phase, no. (%) 29/60 (48) 14/28 (50) 
Gastrointestinal involvement, no. (%) 15/29 (52) 11/23 (48) 
MIPI, no. (%)   
    Low 33/60 (55) NA 
    Intermediate 19/60 (32) NA 
    High 8/60 (13) NA 

NA indicates not applicable.

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