Patient characteristics
| Patient characteristics . | ALL1 . | ALL2 . | ALL3 . | ALL4 . | ALL5 . | ALL6 . | ALL7 . | ALL8 . | ALL9 . | ALL10 . | ALL11 . | ALL12 . | ALL13 . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Age, y | 2,9 | 1,8 | 1,8 | 8 | 14,5 | 5 | 4,4 | 12,1 | 3,5 | 15,6 | 8 | 3,4 | 3,8 |
| Sex | female | female | male | female | female | female | male | female | Female | female | male | female | male |
| Relapse | no | no | no | no | no | yes | no | no | No | no | no | no | no |
| Immuno-phenotype | pre-B | common-B | common-B | pre-B | common-B | common-B | common-B | pre-B | pre-B | common-B | pre-B | pre-B | pre-B |
| Cytogenetics | t(12;21)(p13;q22) | normal karyotype | normal karyotype | hyperdiploid | t(9;22) | normal karyotype | hyperdiploid | normal karyotype | normal karyotype | t(12;21)t(5;17) | normal karyotype | t(12;21)(p13;q22) | hyperdiploid |
| Residual disease at d 15 | 2 × 10−4 | 17.3 × 10−2 | 2 × 10−3 | 15.9 × 10−2 | 42 × 10−2 | not performed | 7 × 10−4 | 5 × 10−5 | 4 × 10−3 | 30 × 10−2 | 1 × 10−4 | 1.1 × 10−2 | 4.4 × 10−3 |
| Residual disease at d 29 | no MRD | 4.2 × 10−3 | no MRD | 1.9 × 10−2 | 27 × 10−2 | no MRD | 3 × 10−4 | no MRD | no MRD | 7.3 × 10−3 | no MRD | 3 × 10−4 | 1 × 10−4 |
| Patient characteristics . | ALL1 . | ALL2 . | ALL3 . | ALL4 . | ALL5 . | ALL6 . | ALL7 . | ALL8 . | ALL9 . | ALL10 . | ALL11 . | ALL12 . | ALL13 . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Age, y | 2,9 | 1,8 | 1,8 | 8 | 14,5 | 5 | 4,4 | 12,1 | 3,5 | 15,6 | 8 | 3,4 | 3,8 |
| Sex | female | female | male | female | female | female | male | female | Female | female | male | female | male |
| Relapse | no | no | no | no | no | yes | no | no | No | no | no | no | no |
| Immuno-phenotype | pre-B | common-B | common-B | pre-B | common-B | common-B | common-B | pre-B | pre-B | common-B | pre-B | pre-B | pre-B |
| Cytogenetics | t(12;21)(p13;q22) | normal karyotype | normal karyotype | hyperdiploid | t(9;22) | normal karyotype | hyperdiploid | normal karyotype | normal karyotype | t(12;21)t(5;17) | normal karyotype | t(12;21)(p13;q22) | hyperdiploid |
| Residual disease at d 15 | 2 × 10−4 | 17.3 × 10−2 | 2 × 10−3 | 15.9 × 10−2 | 42 × 10−2 | not performed | 7 × 10−4 | 5 × 10−5 | 4 × 10−3 | 30 × 10−2 | 1 × 10−4 | 1.1 × 10−2 | 4.4 × 10−3 |
| Residual disease at d 29 | no MRD | 4.2 × 10−3 | no MRD | 1.9 × 10−2 | 27 × 10−2 | no MRD | 3 × 10−4 | no MRD | no MRD | 7.3 × 10−3 | no MRD | 3 × 10−4 | 1 × 10−4 |
MRD, minimal residual disease.