Frequency of lymphocytic infiltrate in peripheral organs of aged WT, CCX-CKR−/−, and CCR7−/− mice
| Genotype . | Submandibular gland . | Liver . | Kidney . |
|---|---|---|---|
| WT | 4/16 (25%) | 3/16 (18.8%) | 1/16 (6.3%) |
| CCX-CKR−/− | 13/14 (92.9%)* | 7/12 (58.3%)† | 4/12 (33.3%) |
| CCR7−/− | 7/7 (100%)‡ | 6/6 (100%)§ | 0/6 (0%) |
| Genotype . | Submandibular gland . | Liver . | Kidney . |
|---|---|---|---|
| WT | 4/16 (25%) | 3/16 (18.8%) | 1/16 (6.3%) |
| CCX-CKR−/− | 13/14 (92.9%)* | 7/12 (58.3%)† | 4/12 (33.3%) |
| CCR7−/− | 7/7 (100%)‡ | 6/6 (100%)§ | 0/6 (0%) |
WT and CCX-CKR−/− mice are 8-10 months of age, and CCR7−/− mice are 6.5-11 months of age.
P = .0002, compared with WT (2-tailed Fisher exact test).
P = .0497, compared with WT (2-tailed Fisher exact test).
P = .0013, compared with WT (2-tailed Fisher exact test).
P = .0011, compared with WT (2-tailed Fisher exact test).