Patient and disease characteristics (n = 1937)
Characteristic, N | |
Median age at transplantation, y (range) | 47.0 (18.9-76.4) |
Patient sex (male/female; 5 missing data) | 1108/824 |
Donor sex (male/female; 68 missing data) | 1161/708 |
RIC/myeloablative (29 missing data) | 825/1083 |
Related/unrelated donor (12 missing data) | 946/979 |
BM/ PBSCs source (14 missing data) | 457/1466 |
High-/low-risk disease group | 1355/582 |
Diagnoses, n (%) | |
AML | 702 (36.2) |
ALL | 312 (16.1) |
CML | 73 (3.8) |
MDS | 199 (10.3) |
NHL | 229 (11.8) |
HD | 126 (6.5) |
MM | 143 (7.4) |
CLL | 58 (3.0) |
Nonmalignant hematologic | 95 (4.9) |
Comorbidities, n (%) | |
Arrhythmia | 24 (1) |
Cardiac | 71 (4) |
Inflammatory bowel disease | 17 (< 1) |
Diabetes | 81 (4) |
Cerebrovascular disease | 12 (< 1) |
Psychiatric disturbance | 57 (3) |
Hepatic (mild/moderate-severe) | 101 (5)/25 (1) |
Obesity | 82 (4) |
Infection | 212 (11) |
Rheumatologic | 18 (1) |
Peptic ulcer | 16 (< 1) |
Renal (moderate to severe) | 21 (1) |
Pulmonary (moderate to severe) | 199 (10)/113 (6) |
Prior solid tumor | 91 (5) |
Heart valve disease | 27 (1) |
Characteristic, N | |
Median age at transplantation, y (range) | 47.0 (18.9-76.4) |
Patient sex (male/female; 5 missing data) | 1108/824 |
Donor sex (male/female; 68 missing data) | 1161/708 |
RIC/myeloablative (29 missing data) | 825/1083 |
Related/unrelated donor (12 missing data) | 946/979 |
BM/ PBSCs source (14 missing data) | 457/1466 |
High-/low-risk disease group | 1355/582 |
Diagnoses, n (%) | |
AML | 702 (36.2) |
ALL | 312 (16.1) |
CML | 73 (3.8) |
MDS | 199 (10.3) |
NHL | 229 (11.8) |
HD | 126 (6.5) |
MM | 143 (7.4) |
CLL | 58 (3.0) |
Nonmalignant hematologic | 95 (4.9) |
Comorbidities, n (%) | |
Arrhythmia | 24 (1) |
Cardiac | 71 (4) |
Inflammatory bowel disease | 17 (< 1) |
Diabetes | 81 (4) |
Cerebrovascular disease | 12 (< 1) |
Psychiatric disturbance | 57 (3) |
Hepatic (mild/moderate-severe) | 101 (5)/25 (1) |
Obesity | 82 (4) |
Infection | 212 (11) |
Rheumatologic | 18 (1) |
Peptic ulcer | 16 (< 1) |
Renal (moderate to severe) | 21 (1) |
Pulmonary (moderate to severe) | 199 (10)/113 (6) |
Prior solid tumor | 91 (5) |
Heart valve disease | 27 (1) |
RIC indicates reduced-intensity/nonmyeloablative conditioning regimen; PBSCs, peripheral blood stem cells; ALL, acute lymphoid leukemia; AML, acute myeloid leukemia; MDS, myelodisplastic syndrome; CML, chronic myeloid leukemia; NHL, non-Hodgkin lymphoma; HD, Hodgkin disease; MM, multiple myeloma; and CLL, chronic lymphocytic leukemia.