Microvascular and hemodynamic parameters in TNF-α–treated postcapillary venules of the cremaster muscle
| Mouse genotype . | n . | Venules, n . | Vessel diameter, μm . | Centerline velocity, μm/s . | Wall shear rate, 1/s . | Systemic leukocyte counts, cells/μL . |
|---|---|---|---|---|---|---|
| Wild-type | 6 | 21 | 30 ± 1 | 1600 ± 100 | 1300 ± 80 | 2800 ± 400 |
| St3gal6Δ/Δ | 6 | 22 | 30 ± 1 | 1300 ± 70 | 1100 ± 60 | 3100 ± 400 |
| St3gal4Δ/ΔSt3gal6Δ/Δ | 8 | 25 | 29 ± 1 | 1400 ± 200 | 1200 ± 200 | 3100 ± 200 |
| Mouse genotype . | n . | Venules, n . | Vessel diameter, μm . | Centerline velocity, μm/s . | Wall shear rate, 1/s . | Systemic leukocyte counts, cells/μL . |
|---|---|---|---|---|---|---|
| Wild-type | 6 | 21 | 30 ± 1 | 1600 ± 100 | 1300 ± 80 | 2800 ± 400 |
| St3gal6Δ/Δ | 6 | 22 | 30 ± 1 | 1300 ± 70 | 1100 ± 60 | 3100 ± 400 |
| St3gal4Δ/ΔSt3gal6Δ/Δ | 8 | 25 | 29 ± 1 | 1400 ± 200 | 1200 ± 200 | 3100 ± 200 |
Vessel diameter, centerline velocity, wall shear rate, and systemic leukocyte counts are presented as mean ± SEM of all investigated venules.