Table 1

Frequencies and RR for response according to KIR genotype

n (%)RR for CCyRRR for MMR
K2DL2  P = .83 P = .50 
    Negative 65 (50) 
    Positive 65 (50) 0.963 0.869 
K2DL5A  P = .17 P = .77 
    Negative 94 (72.3) 
    Positive 36 (27.7) 1.313 0.936 
K2DL5B002  P = .17 P = .88 
    Negative 98 (75.4) 
    Positive 32 (24.6) 1.318 0.951 
K2DL5B003*  P = .17 P = .78 
    Negative 96 (73.8) 
    Positive 33 (25.4) 1.316 0.956 
K2DS1  P = .09 P = .99 
    Negative 93 (71.5) 
    Positive 37 (28.5) 1.398 1.003 
K2DS2  P = .87 P = .61 
    Negative 64 (49.2) 
    Positive 66 (50.8) 0.970 0.899 
K2DS3  P = .21 P = .10 
    Negative 96 (73.8) 
    Positive 34 (26.2) 0.768 0.669 
K2DS4 (alleles 0010101-0010103,00102/002)  P = .97 P = .75 
    Negative 73 (56.2) 
    Positive 57 (43.8) 0.994 0.935 
K2DS4 (alleles 003/004/006/007)  P = .65 P = .41 
    Negative 27 (20.8) 
    Positive 103 (79.2) 1.106 1.247 
K2DS5  P = .26 P = .76 
    Negative 96 (73.8) 
    Positive 34 (26.2) 1.256 1.073 
K3DS1  P = .08 P = .95 
    Negative 89 (68.5) 
    Positive 41 (31.5) 1.413 1.013 
n (%)RR for CCyRRR for MMR
K2DL2  P = .83 P = .50 
    Negative 65 (50) 
    Positive 65 (50) 0.963 0.869 
K2DL5A  P = .17 P = .77 
    Negative 94 (72.3) 
    Positive 36 (27.7) 1.313 0.936 
K2DL5B002  P = .17 P = .88 
    Negative 98 (75.4) 
    Positive 32 (24.6) 1.318 0.951 
K2DL5B003*  P = .17 P = .78 
    Negative 96 (73.8) 
    Positive 33 (25.4) 1.316 0.956 
K2DS1  P = .09 P = .99 
    Negative 93 (71.5) 
    Positive 37 (28.5) 1.398 1.003 
K2DS2  P = .87 P = .61 
    Negative 64 (49.2) 
    Positive 66 (50.8) 0.970 0.899 
K2DS3  P = .21 P = .10 
    Negative 96 (73.8) 
    Positive 34 (26.2) 0.768 0.669 
K2DS4 (alleles 0010101-0010103,00102/002)  P = .97 P = .75 
    Negative 73 (56.2) 
    Positive 57 (43.8) 0.994 0.935 
K2DS4 (alleles 003/004/006/007)  P = .65 P = .41 
    Negative 27 (20.8) 
    Positive 103 (79.2) 1.106 1.247 
K2DS5  P = .26 P = .76 
    Negative 96 (73.8) 
    Positive 34 (26.2) 1.256 1.073 
K3DS1  P = .08 P = .95 
    Negative 89 (68.5) 
    Positive 41 (31.5) 1.413 1.013 

The prognostic influence of an individual KIR gene was analyzed only if the gene prevalence was greater than 10% of the population. P values < .003 are considered as significant (multiple testing correction).

KIR indicates killer immunoglobulin-like receptors; MMR, major molecular response; CCyR, complete cytogenetic response; and RR, relative risk.

*

One patient had missing data.

or Create an Account

Close Modal
Close Modal