Frequencies and RR for response according to KIR genotype
. | n (%) . | RR for CCyR . | RR for MMR . |
---|---|---|---|
K2DL2 | P = .83 | P = .50 | |
Negative | 65 (50) | 1 | 1 |
Positive | 65 (50) | 0.963 | 0.869 |
K2DL5A | P = .17 | P = .77 | |
Negative | 94 (72.3) | 1 | 1 |
Positive | 36 (27.7) | 1.313 | 0.936 |
K2DL5B002 | P = .17 | P = .88 | |
Negative | 98 (75.4) | 1 | 1 |
Positive | 32 (24.6) | 1.318 | 0.951 |
K2DL5B003* | P = .17 | P = .78 | |
Negative | 96 (73.8) | 1 | 1 |
Positive | 33 (25.4) | 1.316 | 0.956 |
K2DS1 | P = .09 | P = .99 | |
Negative | 93 (71.5) | 1 | 1 |
Positive | 37 (28.5) | 1.398 | 1.003 |
K2DS2 | P = .87 | P = .61 | |
Negative | 64 (49.2) | 1 | 1 |
Positive | 66 (50.8) | 0.970 | 0.899 |
K2DS3 | P = .21 | P = .10 | |
Negative | 96 (73.8) | 1 | 1 |
Positive | 34 (26.2) | 0.768 | 0.669 |
K2DS4 (alleles 0010101-0010103,00102/002) | P = .97 | P = .75 | |
Negative | 73 (56.2) | 1 | 1 |
Positive | 57 (43.8) | 0.994 | 0.935 |
K2DS4 (alleles 003/004/006/007) | P = .65 | P = .41 | |
Negative | 27 (20.8) | 1 | 1 |
Positive | 103 (79.2) | 1.106 | 1.247 |
K2DS5 | P = .26 | P = .76 | |
Negative | 96 (73.8) | 1 | 1 |
Positive | 34 (26.2) | 1.256 | 1.073 |
K3DS1 | P = .08 | P = .95 | |
Negative | 89 (68.5) | 1 | 1 |
Positive | 41 (31.5) | 1.413 | 1.013 |
. | n (%) . | RR for CCyR . | RR for MMR . |
---|---|---|---|
K2DL2 | P = .83 | P = .50 | |
Negative | 65 (50) | 1 | 1 |
Positive | 65 (50) | 0.963 | 0.869 |
K2DL5A | P = .17 | P = .77 | |
Negative | 94 (72.3) | 1 | 1 |
Positive | 36 (27.7) | 1.313 | 0.936 |
K2DL5B002 | P = .17 | P = .88 | |
Negative | 98 (75.4) | 1 | 1 |
Positive | 32 (24.6) | 1.318 | 0.951 |
K2DL5B003* | P = .17 | P = .78 | |
Negative | 96 (73.8) | 1 | 1 |
Positive | 33 (25.4) | 1.316 | 0.956 |
K2DS1 | P = .09 | P = .99 | |
Negative | 93 (71.5) | 1 | 1 |
Positive | 37 (28.5) | 1.398 | 1.003 |
K2DS2 | P = .87 | P = .61 | |
Negative | 64 (49.2) | 1 | 1 |
Positive | 66 (50.8) | 0.970 | 0.899 |
K2DS3 | P = .21 | P = .10 | |
Negative | 96 (73.8) | 1 | 1 |
Positive | 34 (26.2) | 0.768 | 0.669 |
K2DS4 (alleles 0010101-0010103,00102/002) | P = .97 | P = .75 | |
Negative | 73 (56.2) | 1 | 1 |
Positive | 57 (43.8) | 0.994 | 0.935 |
K2DS4 (alleles 003/004/006/007) | P = .65 | P = .41 | |
Negative | 27 (20.8) | 1 | 1 |
Positive | 103 (79.2) | 1.106 | 1.247 |
K2DS5 | P = .26 | P = .76 | |
Negative | 96 (73.8) | 1 | 1 |
Positive | 34 (26.2) | 1.256 | 1.073 |
K3DS1 | P = .08 | P = .95 | |
Negative | 89 (68.5) | 1 | 1 |
Positive | 41 (31.5) | 1.413 | 1.013 |
The prognostic influence of an individual KIR gene was analyzed only if the gene prevalence was greater than 10% of the population. P values < .003 are considered as significant (multiple testing correction).
KIR indicates killer immunoglobulin-like receptors; MMR, major molecular response; CCyR, complete cytogenetic response; and RR, relative risk.
One patient had missing data.