Table 3 PFS and OS based on angiogenic... | American Society of Hematology

Table 3

PFS and OS based on angiogenic biomarker levels

	Level	No. at risk	No. of events	Kaplan-Meier estimates		HR (95% CI)	P
	Level	No. at risk	No. of events	1-y, %	2-y, %	HR (95% CI)	P
PFS
All patients		64	22	77	69
Urine VEGF	≤ Median	28	5	89	86	3.25 (1.15-9.12)	.03
	> Median	28	13	64	54
Plasma VCAM	≤ Median	26	5	88	85	2.56 (0.89-7.38)	.08
	> Median	26	11	65	58
Plasma VEGF	≤ Median	26	9	77	69	0.81 (0.30-2.17)	.67
	> Median	26	7	77	73
CECs	≤ Median	27	6	81	81	1.93 (0.70-5.32)	.20
	> Median	26	10	73	62
OS
All patients		64	15	86	80
Urine VEGF	≤ Median	28	4	96	93	2.89 (0.90-9.22)	.07
	> Median	28	10	75	64
Plasma VCAM	≤ Median	26	3	92	92	3.75 (1.03-13.7)	.04
	> Median	26	10	77	65
Plasma VEGF	≤ Median	26	6	88	81	1.23 (0.41-3.66)	.71
	> Median	26	7	81	77
CECs	≤ Median	27	5	89	85	1.41 (0.44-4.49)	.57
	> Median	26	7	85	77

	Level	No. at risk	No. of events	Kaplan-Meier estimates		HR (95% CI)	P
	Level	No. at risk	No. of events	1-y, %	2-y, %	HR (95% CI)	P
PFS
All patients		64	22	77	69
Urine VEGF	≤ Median	28	5	89	86	3.25 (1.15-9.12)	.03
	> Median	28	13	64	54
Plasma VCAM	≤ Median	26	5	88	85	2.56 (0.89-7.38)	.08
	> Median	26	11	65	58
Plasma VEGF	≤ Median	26	9	77	69	0.81 (0.30-2.17)	.67
	> Median	26	7	77	73
CECs	≤ Median	27	6	81	81	1.93 (0.70-5.32)	.20
	> Median	26	10	73	62
OS
All patients		64	15	86	80
Urine VEGF	≤ Median	28	4	96	93	2.89 (0.90-9.22)	.07
	> Median	28	10	75	64
Plasma VCAM	≤ Median	26	3	92	92	3.75 (1.03-13.7)	.04
	> Median	26	10	77	65
Plasma VEGF	≤ Median	26	6	88	81	1.23 (0.41-3.66)	.71
	> Median	26	7	81	77
CECs	≤ Median	27	5	89	85	1.41 (0.44-4.49)	.57
	> Median	26	7	85	77

Events are relapse or death for PFS, and deaths for OS.