Table 1

Cell numbers and percentages in BM, spleen, iLNs, and PB

WTSpi-B−/−
BM (n = 8) 
    Total cells, × 10−7 2.4 ± 0.3 2.6 ± 0.5 
    pDCs, × 10−5 3.7 ± 1.1 2.2 ± 1.1* 
    pDCs, % 1.5 ± 0.4 0.9 ± 0.3† 
    B cells, × 10−6 3.1 ± 1.1 3.7 ± 2.3 
    B cells, % 12.7 ± 4.6 13.7 ± 6.8 
Spleen (n = 8) 
    Total cells, × 10−7 3.3 ± 0.7 3.2 ± 0.9 
    pDCs, × 10−5 1.1 ± 0.4 2.3 ± 0.7† 
    pDCs, % 0.3 ± 0.1 0.7 ± 0.1‡ 
    cDCs, × 10−5 5.6 ± 1.4 7.2 ± 1.5* 
    cDCs, % 1.7 ± 0.2 2.3 ± 0.2‡ 
    B cells, × 10−7 1.6 ± 0.4 1.5 ± 0.5 
    B cells, % 47.3 ± 4.5 47.3 ± 5.7 
iLNs (n = 6) 
    Total cells, × 10−6 1.7 ± 0.9 0.8 ± 0.4* 
    pDCs, × 10−4 0.5 ± 0.2 1.3 ± 0.6* 
    pDCs, % 0.3 ± 0.1 1.5 ± 0.4‡ 
    cDCs, × 10−3 8.0 ± 4.3 6.2 ± 4.1 
    cDCs, % 0.6 ± 0.2 0.6 ± 0.2 
    B cells, × 10−5 3.9 ± 2.4 2.1 ± 0.9 
    B cells, % 22.2 ± 4.2 25.7 ± 3.4 
PB (n = 8) 
    Total cells, × 10−6 2.4 ± 0.7 2.5 ± 0.8 
    pDCs, × 10−2 1.7 ± 1.3 5.9 ± 4.8* 
    pDCs, % 0.1 ± 0.1 0.2 ± 0.2* 
    B cells, × 10−5 5.3 ± 2.3 5.7 ± 1.9 
    B cells, % 21.4 ± 3.3 22.9 ± 3.3 
WTSpi-B−/−
BM (n = 8) 
    Total cells, × 10−7 2.4 ± 0.3 2.6 ± 0.5 
    pDCs, × 10−5 3.7 ± 1.1 2.2 ± 1.1* 
    pDCs, % 1.5 ± 0.4 0.9 ± 0.3† 
    B cells, × 10−6 3.1 ± 1.1 3.7 ± 2.3 
    B cells, % 12.7 ± 4.6 13.7 ± 6.8 
Spleen (n = 8) 
    Total cells, × 10−7 3.3 ± 0.7 3.2 ± 0.9 
    pDCs, × 10−5 1.1 ± 0.4 2.3 ± 0.7† 
    pDCs, % 0.3 ± 0.1 0.7 ± 0.1‡ 
    cDCs, × 10−5 5.6 ± 1.4 7.2 ± 1.5* 
    cDCs, % 1.7 ± 0.2 2.3 ± 0.2‡ 
    B cells, × 10−7 1.6 ± 0.4 1.5 ± 0.5 
    B cells, % 47.3 ± 4.5 47.3 ± 5.7 
iLNs (n = 6) 
    Total cells, × 10−6 1.7 ± 0.9 0.8 ± 0.4* 
    pDCs, × 10−4 0.5 ± 0.2 1.3 ± 0.6* 
    pDCs, % 0.3 ± 0.1 1.5 ± 0.4‡ 
    cDCs, × 10−3 8.0 ± 4.3 6.2 ± 4.1 
    cDCs, % 0.6 ± 0.2 0.6 ± 0.2 
    B cells, × 10−5 3.9 ± 2.4 2.1 ± 0.9 
    B cells, % 22.2 ± 4.2 25.7 ± 3.4 
PB (n = 8) 
    Total cells, × 10−6 2.4 ± 0.7 2.5 ± 0.8 
    pDCs, × 10−2 1.7 ± 1.3 5.9 ± 4.8* 
    pDCs, % 0.1 ± 0.1 0.2 ± 0.2* 
    B cells, × 10−5 5.3 ± 2.3 5.7 ± 1.9 
    B cells, % 21.4 ± 3.3 22.9 ± 3.3 

Percentages and numbers of pDCs (CD19−CD11c+B220+BST2+), cDCs (CD19−CD11c+B220−), and B cells (CD19+CD11c−) among total live cells are shown. Data represent means ± SD.

*

P < .05.

†

P < .01.

‡

P < .001.

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