Receiver operating characteristic curve analysis
| Phenotype . | Age at first TTP episode requiring FFP < 18 y . | Annual rate of TTP episodes > 1 . | Regular FFP prophylaxis . |
|---|---|---|---|
| ADAMTS13 activity cutoff, % | < 2.74 | < 1.61 | < 2.74 |
| Area under the curve (95% CI) | 0.880 (0.746-1.013) | 0.930 (0.829-1.032) | 0.752 (0.564-0.941) |
| P | .001 | .003 | .023 |
| Sensitivity | 92.3% | 78.3% | 70.6% |
| Specificity | 81.3% | 100% | 75.0% |
| OR (95% CI) | 52.00 (4.74-570.53) | 1.615 × 109 (NC) | 7.20 (1.35-38.33) |
| Phenotype . | Age at first TTP episode requiring FFP < 18 y . | Annual rate of TTP episodes > 1 . | Regular FFP prophylaxis . |
|---|---|---|---|
| ADAMTS13 activity cutoff, % | < 2.74 | < 1.61 | < 2.74 |
| Area under the curve (95% CI) | 0.880 (0.746-1.013) | 0.930 (0.829-1.032) | 0.752 (0.564-0.941) |
| P | .001 | .003 | .023 |
| Sensitivity | 92.3% | 78.3% | 70.6% |
| Specificity | 81.3% | 100% | 75.0% |
| OR (95% CI) | 52.00 (4.74-570.53) | 1.615 × 109 (NC) | 7.20 (1.35-38.33) |
OR indicates odds ratio; and NC, noncalculable.