Thrombin-generation parameters from analyses of reconstituted PPP time courses
| Mixture . | Clot time, min . | Max rate, nM/min . | Max level, nM . |
|---|---|---|---|
| αTAT parameters | |||
| WB | 3:40 ± 0:18 | 30.1 ± 2.9 | 354 ± 8.42 |
| PPP | 5:35 ± 1:07 | 6.0 ± 0.9 | 79 ± 23 |
| PPP + RBCs | 4:10 ± 0:18 | 21.1 ± 2.0 | 242 ± 16 |
| mTAT parameters | |||
| WB | 3:40 ± 0:18 | 1.2 ± 0.8 | 14.7 ± 11.3 |
| PPP | 5:35 ± 1:07 | 0.4 ± 0.2 | 4.1 ± 2.5 |
| PPP + RBCs | 4:10 ± 0:18 | 0.7 ± 0.2 | 9.1 ± 2.5 |
| Mixture . | Clot time, min . | Max rate, nM/min . | Max level, nM . |
|---|---|---|---|
| αTAT parameters | |||
| WB | 3:40 ± 0:18 | 30.1 ± 2.9 | 354 ± 8.42 |
| PPP | 5:35 ± 1:07 | 6.0 ± 0.9 | 79 ± 23 |
| PPP + RBCs | 4:10 ± 0:18 | 21.1 ± 2.0 | 242 ± 16 |
| mTAT parameters | |||
| WB | 3:40 ± 0:18 | 1.2 ± 0.8 | 14.7 ± 11.3 |
| PPP | 5:35 ± 1:07 | 0.4 ± 0.2 | 4.1 ± 2.5 |
| PPP + RBCs | 4:10 ± 0:18 | 0.7 ± 0.2 | 9.1 ± 2.5 |
Thrombin- and meizothrombin-generation parameters are from Figure 6. The clot time, maximum (max) rate of αTAT and mTAT formation and max level of αTAT and mTAT formation were calculated from the αTAT and mTAT ELISA data. Data are shown as the means ± SEM (n = 3).