Thrombin-generation parameters from analyses of reconstituted PRP time courses
Mixture . | Clot time, min . | αTAT max rate, nM/min . | αTAT max level, nM . | αTAT max % of WB . |
---|---|---|---|---|
WB | 4:09 ± 0:19 | 47.2 ± 7.2 | 444 ± 49.6 | 100 |
PRP + PPP | 7:54 ± 1:12 | 38 ± 4.9 | 267 ± 19.7 | 60 |
PRP + buffy coat | 7:46 ± 1:35 | 32.4 ± 6.3 | 335 ± 53.7 | 75 |
PRP + RBCs | 4:47 ± 0:25 | 48.4 ± 7.0 | 451 ± 51.4 | 101 |
Mixture . | Clot time, min . | αTAT max rate, nM/min . | αTAT max level, nM . | αTAT max % of WB . |
---|---|---|---|---|
WB | 4:09 ± 0:19 | 47.2 ± 7.2 | 444 ± 49.6 | 100 |
PRP + PPP | 7:54 ± 1:12 | 38 ± 4.9 | 267 ± 19.7 | 60 |
PRP + buffy coat | 7:46 ± 1:35 | 32.4 ± 6.3 | 335 ± 53.7 | 75 |
PRP + RBCs | 4:47 ± 0:25 | 48.4 ± 7.0 | 451 ± 51.4 | 101 |
The thrombin-generation parameters clot time, maximum (max) rate of αTAT formation, and max level of αTAT formation are presented. Data are presented as means ± SEM (n = 5).