Frequency of HLA-DPA1 and DPB1 alleles in ALL cases and controls in non-Hispanic white and Hispanic children, NCCLS, 1995-2008
| . | Non-Hispanic white . | Hispanic . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Cases . | Controls . | P . | Cases . | Controls . | P . | |||||
| n* . | % . | n* . | % . | n* . | % . | n* . | % . | |||
| DPA1 alleles | ||||||||||
| 01:03 | 427 | 80.6 | 669 | 82.0 | .679 | 492 | 77.1 | 688 | 78.5 | .510 |
| 02:01 | 81 | 15.3 | 111 | 13.6 | .390 | 94 | 14.7 | 136 | 15.5 | .666 |
| 02:02 | 18 | 3.4 | 30 | 3.7 | .883 | 44 | 6.9 | 46 | 5.3 | .217 |
| Others† | 4 | 0.7 | 6 | 0.7 | NA | 8 | 1.3 | 6 | 0.7 | NA |
| Total chromosomes | 530 | 816 | 638 | 876 | ||||||
| DPB1 alleles | ||||||||||
| 01:01 | 36 | 6.8 | 37 | 4.5 | .104 | 35 | 5.5 | 36 | 4.1 | .266 |
| 02:01 | 70 | 13.2 | 116 | 14.2 | .633 | 77 | 12.0 | 97 | 11.0 | .622 |
| 03:01 | 57 | 10.8 | 84 | 10.3 | .789 | 37 | 5.8 | 57 | 6.5 | .595 |
| 04:01 | 206 | 38.9 | 336 | 41.2 | .468 | 155 | 24.2 | 233 | 26.5 | .338 |
| 04:02 | 64 | 12.1 | 96 | 11.8 | .864 | 214 | 33.4 | 290 | 33.0 | .954 |
| 05:01 | 10 | 1.9 | 18 | 2.2 | .845 | 20 | 3.1 | 23 | 2.6 | .638 |
| 10:01 | 11 | 2.1 | 14 | 1.7 | .681 | 6 | 0.9 | 14 | 1.6 | .363 |
| 11:01 | 10 | 1.9 | 21 | 2.6 | .456 | 11 | 1.7 | 17 | 1.9 | .850 |
| 13:01 | 12 | 2.3 | 15 | 1.8 | .696 | 11 | 1.7 | 19 | 2.2 | .593 |
| 14:01 | 6 | 1.1 | 5 | 0.6 | .354 | 20 | 3.1 | 25 | 2.8 | .883 |
| 17:01 | 10 | 1.9 | 12 | 1.5 | .666 | 20 | 3.1 | 24 | 2.7 | .751 |
| Others† | 38 | 7.1 | 62 | 7.6 | NA | 34 | 5.3 | 45 | 5.1 | NA |
| Total chromosomes | 530 | 816 | 640 | 880 | ||||||
| . | Non-Hispanic white . | Hispanic . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Cases . | Controls . | P . | Cases . | Controls . | P . | |||||
| n* . | % . | n* . | % . | n* . | % . | n* . | % . | |||
| DPA1 alleles | ||||||||||
| 01:03 | 427 | 80.6 | 669 | 82.0 | .679 | 492 | 77.1 | 688 | 78.5 | .510 |
| 02:01 | 81 | 15.3 | 111 | 13.6 | .390 | 94 | 14.7 | 136 | 15.5 | .666 |
| 02:02 | 18 | 3.4 | 30 | 3.7 | .883 | 44 | 6.9 | 46 | 5.3 | .217 |
| Others† | 4 | 0.7 | 6 | 0.7 | NA | 8 | 1.3 | 6 | 0.7 | NA |
| Total chromosomes | 530 | 816 | 638 | 876 | ||||||
| DPB1 alleles | ||||||||||
| 01:01 | 36 | 6.8 | 37 | 4.5 | .104 | 35 | 5.5 | 36 | 4.1 | .266 |
| 02:01 | 70 | 13.2 | 116 | 14.2 | .633 | 77 | 12.0 | 97 | 11.0 | .622 |
| 03:01 | 57 | 10.8 | 84 | 10.3 | .789 | 37 | 5.8 | 57 | 6.5 | .595 |
| 04:01 | 206 | 38.9 | 336 | 41.2 | .468 | 155 | 24.2 | 233 | 26.5 | .338 |
| 04:02 | 64 | 12.1 | 96 | 11.8 | .864 | 214 | 33.4 | 290 | 33.0 | .954 |
| 05:01 | 10 | 1.9 | 18 | 2.2 | .845 | 20 | 3.1 | 23 | 2.6 | .638 |
| 10:01 | 11 | 2.1 | 14 | 1.7 | .681 | 6 | 0.9 | 14 | 1.6 | .363 |
| 11:01 | 10 | 1.9 | 21 | 2.6 | .456 | 11 | 1.7 | 17 | 1.9 | .850 |
| 13:01 | 12 | 2.3 | 15 | 1.8 | .696 | 11 | 1.7 | 19 | 2.2 | .593 |
| 14:01 | 6 | 1.1 | 5 | 0.6 | .354 | 20 | 3.1 | 25 | 2.8 | .883 |
| 17:01 | 10 | 1.9 | 12 | 1.5 | .666 | 20 | 3.1 | 24 | 2.7 | .751 |
| Others† | 38 | 7.1 | 62 | 7.6 | NA | 34 | 5.3 | 45 | 5.1 | NA |
| Total chromosomes | 530 | 816 | 640 | 880 | ||||||
NA indicates not applicable.
Number and percent of chromosomes typing for each allele.
Group of rare HLA-DP alleles < 0.02 frequency in both non-Hispanic white and Hispanic children. Alleles not shown include: DPA1, 01:04, 03:01, and 04:01; and DPB1, 02:02, 102:01, 06:01, 09:01, 15:01, 16:01, 18:01, 19:01, 20:01, 23:01, 26:01, 29:01, 34:01, 40:01, 51:01, 54:01, and 60:01.