Table 2

The effects of haplotypes on MCV, HbF, D50 and % DRBCs

Patient haplotypeNo.MCV, mean ± SD% HbF, mean ± SDα−Thal del, %D50, mean ± SD% DRBCs, mean ± SD
Benin/Benin 200 88.7 ± 9.6* 7.4 ± 5.2* 49*† 1.096 ± 0.003* 13.4 ± 7.7 
Benin/CAR 33 88.1 ± 6.7 7.0 ± 5.5† 42‡ 1.096 ± 0.003 14.8 ± 9.6 
Benin/Cameroon 24 83.8 ± 10.2 5.9 ± 3.7‡ 42 1.095 ± 0.003 9.8 ± 7.5 
Benin/Senegal 31 88.6 ± 9.6 9.6 ± 6.2§ 35§ 1.096 ± 0.003 13.3 ± 7.8 
CAR/CAR 134 83.2 ± 9.9*†‡ 5.7 ± 4.4*§‖ 64*‡§ 1.095 ± 0.003*† 11.3 ± 7.4 
Senegal/Senegal 38 91.5 ± 11.1† 11.7 ± 5.9*†‡‖¶ 29*† 1.097 ± 0.002† 13.0 ± 7.2 
Other 40 89.2 ± 8.6‡ 7.2 ± 4.7¶ 50 1.096 ± 0.003 13.2 ± 7.8 
Patient haplotypeNo.MCV, mean ± SD% HbF, mean ± SDα−Thal del, %D50, mean ± SD% DRBCs, mean ± SD
Benin/Benin 200 88.7 ± 9.6* 7.4 ± 5.2* 49*† 1.096 ± 0.003* 13.4 ± 7.7 
Benin/CAR 33 88.1 ± 6.7 7.0 ± 5.5† 42‡ 1.096 ± 0.003 14.8 ± 9.6 
Benin/Cameroon 24 83.8 ± 10.2 5.9 ± 3.7‡ 42 1.095 ± 0.003 9.8 ± 7.5 
Benin/Senegal 31 88.6 ± 9.6 9.6 ± 6.2§ 35§ 1.096 ± 0.003 13.3 ± 7.8 
CAR/CAR 134 83.2 ± 9.9*†‡ 5.7 ± 4.4*§‖ 64*‡§ 1.095 ± 0.003*† 11.3 ± 7.4 
Senegal/Senegal 38 91.5 ± 11.1† 11.7 ± 5.9*†‡‖¶ 29*† 1.097 ± 0.002† 13.0 ± 7.2 
Other 40 89.2 ± 8.6‡ 7.2 ± 4.7¶ 50 1.096 ± 0.003 13.2 ± 7.8 

The symbols indicate significant differences between the means sharing the same symbol. For example, the mean of MCV for SS patients with Benin/Benin haplotype is significantly different from the mean of patients with CAR/CAR haplotype. The statistical significance, defined as P < .05, was obtained with ANOVA test and Tukey adjustment for multiple comparisons, and χ2 test for α status when authorized.

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