Patients with ASCIE
| SCD/Non-SCD . | Age, y/sex . | Etiology of anemia . | Hgb, g/dL . | Transfusion . | ICU transfer . | Neurologic examination . | DWI/ADC . | Initial FLAIR . | Correlate on follow-up MRI . | MRA . |
|---|---|---|---|---|---|---|---|---|---|---|
| Non-SCD | 7/M | Autoimmune hemolysis | 3.7 | + | + | Abn | +/+ | + | ND | ND |
| Non-SCD | 9/M | Aplastic anemia | 2.4 | + | + | Normal | +/+ | − | − | Normal |
| SCD | 10/F | Aplastic crisis | 2.9 | + | + | ND | +/+ | + | + | Normal |
| SCD | 6/M | Acute chest syndrome | 4.1 | + | − | Normal | +/+ | + | + | Subtle vascular irregularity ipsilateral ICA/MCA |
| SCD | 11/M | Aplastic crisis and splenic sequestration | 2.2 | + | − | Abn | +/+ | − | ND | ND |
| SCD | 5/M | Aplastic crisis | 3.3 | + | − | Normal | +/+ | + | + | Normal |
| SCD/Non-SCD . | Age, y/sex . | Etiology of anemia . | Hgb, g/dL . | Transfusion . | ICU transfer . | Neurologic examination . | DWI/ADC . | Initial FLAIR . | Correlate on follow-up MRI . | MRA . |
|---|---|---|---|---|---|---|---|---|---|---|
| Non-SCD | 7/M | Autoimmune hemolysis | 3.7 | + | + | Abn | +/+ | + | ND | ND |
| Non-SCD | 9/M | Aplastic anemia | 2.4 | + | + | Normal | +/+ | − | − | Normal |
| SCD | 10/F | Aplastic crisis | 2.9 | + | + | ND | +/+ | + | + | Normal |
| SCD | 6/M | Acute chest syndrome | 4.1 | + | − | Normal | +/+ | + | + | Subtle vascular irregularity ipsilateral ICA/MCA |
| SCD | 11/M | Aplastic crisis and splenic sequestration | 2.2 | + | − | Abn | +/+ | − | ND | ND |
| SCD | 5/M | Aplastic crisis | 3.3 | + | − | Normal | +/+ | + | + | Normal |
ASCIE indicates acute silent cerebral ischemic event; SCD, sickle cell disease; Hgb, hemoglobin; ICU, intensive care unit; DWI, diffusion-weighted imaging; ADC, apparent diffusion coefficient; FLAIR, fluid-attenuated inversion recovery; MRI, magnetic resonance imaging; MRA, magnetic resonance angiography; F, female; M, male; Abn, abnormal; ND, not done; ICA, internal carotid artery; and MCA, middle cerebral artery.