Current status of interim PET-directed ongoing trials in HL
| Group/study . | Reference . | Stage . | Recruited/target . | iPET+ . | iPET− . | Interpretation rules . |
|---|---|---|---|---|---|---|
| GITIL/HD0607 | 53 | Advanced | 389/450 | 77 (20%) | 312 (80%) | 5PS |
| SWOG/ S0816 | 54 | Advanced | 248/300 | 45 (20%) | 176 (80%) | 5PS |
| GELA/AHL 2011 | 55 | Advanced | 100/798 | — | — | 5PS |
| CR-UK/RATHL | 56 | Advanced | 680/1200 | 106 (16%) | 574 (84%) | 5PS |
| GHSG/HD18 | 57 | Advanced | 1146/1500 | 535 (47%) | 611 (53%) | Modified 5PS |
| FIL/ HD0801 | 58 | Advanced | 291/300 | 70 (24%) | 221 (76%) | IHP |
| RHC/NA | 59 | Early + advanced | 226/660 | 29 (13%) | 197 (87%) | Dynamic |
| EORTC-GELA/H10 | 42 | Early | 124/1797 | 24 (19%) | 100 (81%) | Modified IHP |
| CALGB/50801 | 43 | Bulky early | 17/123 | 4 (31%) | 9 (69%) | 5PS |
| ECOG/2410 | 44 | Bulky early | —/200 | — | — | 5PS |
| CALGB/50604 | 45 | n-bulky early | 75/149 | 5 (9%) | 51 (91%) | 5PS |
| NHS-FT/RAPID | 46 | n-bulky early | 571/575 | 145 (25%) | 426 (75%) | 5PS |
| GHSG/HD16 | 47 | f-Early | —/1100 | — | — | Modified 5PS |
| GHSG/HD17 | 48 | Early rf | —/1100 | — | — | Modified 5PS |
| Group/study . | Reference . | Stage . | Recruited/target . | iPET+ . | iPET− . | Interpretation rules . |
|---|---|---|---|---|---|---|
| GITIL/HD0607 | 53 | Advanced | 389/450 | 77 (20%) | 312 (80%) | 5PS |
| SWOG/ S0816 | 54 | Advanced | 248/300 | 45 (20%) | 176 (80%) | 5PS |
| GELA/AHL 2011 | 55 | Advanced | 100/798 | — | — | 5PS |
| CR-UK/RATHL | 56 | Advanced | 680/1200 | 106 (16%) | 574 (84%) | 5PS |
| GHSG/HD18 | 57 | Advanced | 1146/1500 | 535 (47%) | 611 (53%) | Modified 5PS |
| FIL/ HD0801 | 58 | Advanced | 291/300 | 70 (24%) | 221 (76%) | IHP |
| RHC/NA | 59 | Early + advanced | 226/660 | 29 (13%) | 197 (87%) | Dynamic |
| EORTC-GELA/H10 | 42 | Early | 124/1797 | 24 (19%) | 100 (81%) | Modified IHP |
| CALGB/50801 | 43 | Bulky early | 17/123 | 4 (31%) | 9 (69%) | 5PS |
| ECOG/2410 | 44 | Bulky early | —/200 | — | — | 5PS |
| CALGB/50604 | 45 | n-bulky early | 75/149 | 5 (9%) | 51 (91%) | 5PS |
| NHS-FT/RAPID | 46 | n-bulky early | 571/575 | 145 (25%) | 426 (75%) | 5PS |
| GHSG/HD16 | 47 | f-Early | —/1100 | — | — | Modified 5PS |
| GHSG/HD17 | 48 | Early rf | —/1100 | — | — | Modified 5PS |
— indicates not applicable; 5PS, 5-point scale (Deauville criteria); Modified 5PS, Modified 5-point scale; IHP, International Harmonization Project criteria for end-treatment PET evaluation72 ; Dynamic, dynamic interpretation criteria developed by the Israeli group for interim PET evaluation73 ; and Modified IHP, modified International Harmonization Project criteria for end-therapy PET evaluation.