Table 1 Demographic and clinical... | American Society of Hematology

Table 1

Demographic and clinical characteristics of children in the SIT Trial by (GT)_n genotype class

Characteristic*	S/S† (n = 35)		S/L + L/L† (n = 907)		P
Characteristic*	N	Mean or %	N	Mean or %	P
Age at registration	35	9.2	907	9	.79
Male	35	60	914	51.5	.32
Ever had asthma	35	34.3	907	25.1	.22
Steady-state white blood count, count/μL	34	11 811	894	12 648	.39‡
Steady-state hemoglobin, g/dL	35	8	906	8.1	.81
Steady-state reticulocytes	32	13.7	889	12	.08
Total bilirubin, mg/dL	33	3.7	835	3.8	.94
Fetal hemoglobin	32	14	895	12.7	.01‡

Characteristic*	S/S† (n = 35)		S/L + L/L† (n = 907)		P
Characteristic*	N	Mean or %	N	Mean or %	P
Age at registration	35	9.2	907	9	.79
Male	35	60	914	51.5	.32
Ever had asthma	35	34.3	907	25.1	.22
Steady-state white blood count, count/μL	34	11 811	894	12 648	.39‡
Steady-state hemoglobin, g/dL	35	8	906	8.1	.81
Steady-state reticulocytes	32	13.7	889	12	.08
Total bilirubin, mg/dL	33	3.7	835	3.8	.94
Fetal hemoglobin	32	14	895	12.7	.01‡

Steady-state levels defined at routine clinical well-visit.

HMOX1 (GT)_n allele classes defined by number of repeats: S ≤ 25 repeats; and L > 25 repeats.

P value based on Student t test of log differences.